Evidence map›Paper›PMID 41235012›Full record

ArticleCureus2025

Congenital Varicella Syndrome and Crossed Nonfused Renal Ectopia in a Neonate: A Case Report.

Neha Jain, Vivek Goyal, Sreevidya Sreekantha

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Neha JainPediatrics and Neonatology, Janki Children Hospital, Hisar, IND.
Vivek GoyalPediatrics and Neonatology, Janki Children Hospital, Hisar, IND.
Sreevidya SreekanthaPediatrics and Neonatology, Motherhood Women and Children's Hospital, Bengaluru, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital varicella syndrome (CVS) is a rare consequence of maternal varicella infection during early pregnancy and is characterized by cicatricial skin lesions, neurological impairment, limb hypoplasia, and ocular abnormalities. Renal anomalies are not classical features but may occur. We report a term male neonate, born to a primigravida mother with a history of varicella infection at 12 weeks of gestation. The neonate presented with perinatal asphyxia, seizures, cicatricial skin lesions, and a rare renal anomaly - crossed nonfused renal ectopia (CNRE). The neonate required resuscitation at birth, developed hypoxic-ischemic encephalopathy, and was managed with therapeutic hypothermia and antiepileptics. Radiological imaging revealed CNRE. Both maternal and neonatal varicella IgG serology were positive. The baby improved with supportive management and was discharged in stable condition. To the best of our knowledge, CVS and CNRE are not correlated and represent coincidental, unrelated findings in our case.

Indexed as

cicatricial skin lesionscongenital varicella syndromecrossed nonfused renal ectopiahypoxic-ischemic encephalopathymaternal varicella

Identifiers

PMID41235012
PMCPMC12605621

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.