Evidence map›Paper›PMID 41234986›Full record

ArticleCureus2025

Robotic Whipple for Abnormal Pancreaticobiliary Junction With Recurrent Acute Pancreatitis: A Case Report.

Adam Khader, Sarah-Anne Diamond, Beth Rider, Catherine Vozzo, Munazza Anis, Ronald F Wolf, Jose G Trevino, Leopoldo J Fernandez

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adam KhaderSurgical Oncology, Central Virginia VA Health Care System, Richmond, USA.
Sarah-Anne DiamondSurgical Oncology, Central Virginia VA Health Care System, Richmond, USA.
Beth RiderSurgical Oncology, Central Virginia VA Health Care System, Richmond, USA.
Catherine VozzoGastroenterology, Central Virginia VA Health Care System, Richmond, USA.
Munazza AnisRadiology, Central Virginia VA Health Care System, Richmond, USA.
Ronald F WolfSurgical Oncology, Hoag Family Cancer Institute, Newport Beach, USA.
Jose G TrevinoSurgical Oncology, Virginia Commonwealth University School of Medicine, Richmond, USA.
Leopoldo J FernandezSurgical Oncology, Virginia Commonwealth University School of Medicine, Richmond, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreaticobiliary maljunction (PBM) is a congenital anomaly that predisposes patients to recurrent pancreatitis, choledocholithiasis, and an increased risk of biliary tract malignancy. In patients without biliary dilatation, standard management typically consists of cholecystectomy with endoscopic biliary decompression. However, management can be challenging in patients with refractory recurrent pancreatitis, indeterminate strictures, or progressive ductal changes. We describe a 62-year-old woman with PBM who presented with recurrent acute pancreatitis despite undergoing cholecystectomy, biliary sphincterotomy, and multiple endoscopic retrograde cholangiopancreatography (ERCP) interventions, including stent placements, choledocholithiasis extraction, and SpyGlass-directed biopsies, all of which were negative for malignancy. Over three years, she experienced multiple admissions for pancreatitis, progressive dilation of the common bile duct, and a persistent distal common bile duct stricture. Owing to ongoing symptoms and concern for occult malignancy, she underwent robotic-assisted pancreatoduodenectomy. Intraoperatively, bile-stained stones were identified in the pancreatic duct. Final pathology demonstrated chronic pancreatitis and fibrosis without malignancy. Her postoperative recovery was uneventful, with discharge on postoperative day four and complete resolution of pancreatitis symptoms at several months of follow-up. This case illustrates a rare scenario of PBM-associated recurrent pancreatitis refractory to cholecystectomy and ERCP decompression. The presence of a distal intrapancreatic stricture likely contributed to ongoing symptoms, and the potential for occult malignancy remained despite multiple negative endoscopic biopsies. Robotic pancreatoduodenectomy provided both diagnostic and therapeutic benefits, permitting en bloc resection of the stricture and associated bile duct. Contemporary evidence suggests that robotic pancreatoduodenectomy offers perioperative advantages over open surgery, including reduced blood loss, fewer wound infections, and shorter hospital stays, albeit with longer operative times. These findings align with the favorable course in our patient, who recovered rapidly and remains symptom-free. Robotic pancreatoduodenectomy can be considered a definitive treatment option in select patients with PBM and refractory recurrent pancreatitis, especially in the presence of indeterminate strictures. This approach provides both symptom relief and diagnostic certainty, while offering perioperative benefits compared with open surgery.

Indexed as

ercppancreatic duct stonespancreatobiliary junction anomalyrobotic whipplespyglass

Identifiers

PMID41234986
PMCPMC12606677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.