Evidence map›Paper›PMID 41234886›Full record

ArticleTranslational cancer research2025

Development and validation of a nomogram comprising GLUT1 and clinical characteristics for predicting overall survival in intrahepatic cholangiocarcinoma.

Li-Ping Gong, Yulan Weng, Jing Zhou, Xiangqi Huang, Jian-Ning Chen, Dan He, Yi-Wang Zhang, Yongmei Cui, Jing Liang, Chun-Kui Shao

Abstract read
In one paragraph

Article in Translational cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Integrin αvβ3 is a Potential Therapeutic Target in Cholangiocarcinoma.International journal of medical sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Li-Ping Gong *Department of Pathology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0002-8316-0995
Yulan Weng *Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Jing Zhou *Department of Pathology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xiangqi HuangDepartment of Pathology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jian-Ning ChenDepartment of Pathology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Dan HeDepartment of Pathology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yi-Wang ZhangDepartment of Pathology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yongmei CuiDepartment of Pathology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jing LiangDepartment of Pathology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0001-6219-2763
Chun-Kui ShaoDepartment of Pathology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0002-7083-7522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive malignancy arising from the intrahepatic bile duct epithelium, with increasing global incidence and poor prognosis due to late diagnosis and limited therapeutic options. Current prognostic models such as tumor-node-metastasis (TNM) staging exhibit suboptimal accuracy and lack integration of molecular biomarkers. Our study aims to explore the prognostic significance of Methods: We analyzed Results: TCGA data showed significant upregulation of Conclusions: Our study establishes GLUT1 as an independent prognostic biomarker and provides a clinically applicable tool for individualized risk stratification. While our nomogram shows promise for guiding postoperative management, its single-center design warrants external validation in future multi-center studies.

Indexed as

GLUT1intrahepatic cholangiocarcinoma (iCCA)nomogramprognosissurvival

Identifiers

PMID41234886
PMCPMC12605105

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.