Evidence map›Paper›PMID 41234761›Full record

ReviewAnnals of thoracic medicine

Effects of respiratory muscle training on clinical outcomes in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis.

Xiao-Hui Qi, Hai-Mei Ren, Ning Wang, Xiao-Pan Shi, Xiao-Xing Wang, Ying Wang

Abstract readReview
In one paragraph

Review in Annals of thoracic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Response to "Letter to the Editor: The importance of quantifying training loads and applying exercise principles in respiratory muscle training studies".Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiao-Hui QiRespiratory Intensive Care Unit, Affiliated Hospital of Hebei University, Baoding City, Hebei Province, China.
Hai-Mei RenDepartment of Orthopedics, Affiliated Hospital of Hebei University, Baoding City, Hebei Province, China.
Ning WangDepartment of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Hebei University, Baoding City, Hebei Province, China.
Xiao-Pan ShiDepartment of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Hebei University, Baoding City, Hebei Province, China.
Xiao-Xing WangRespiratory Intensive Care Unit, Affiliated Hospital of Hebei University, Baoding City, Hebei Province, China.
Ying WangDepartment of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Hebei University, Baoding City, Hebei Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effectiveness and clinical significance of respiratory muscle training for chronic obstructive pulmonary disease (COPD) patients remain controversial. Our aim is to systematically review and conduct a meta analysis on the impact of respiratory muscle training on the clinical outcomes of patients with COPD. We systematically searched electronic databases (PubMed, Web of Science, Cochrane Library, and Embase) for randomized controlled trials evaluating the effects of respiratory muscle training on clinical outcomes in COPD patients. We utilized fixed or random effects models to assess the impact of respiratory muscle training on the 6 min walk test (6MWT), dyspnea, pulmonary function, respiratory muscle strength, and quality of life (QOL). Thirteen studies met the inclusion criteria for this review, involving 1178 COPD patients, of whom 588 completed respiratory muscle training. Meta analysis results indicated that respiratory muscle training significantly improved 6MWT (mean difference [MD]: 17.99; 95% confidence interval [CI]: 3.73, 32.26), dyspnea (standardized MD [SMD]: -0.81; 95% CI: -1.28, -0.34), forced expiratory volume in 1 s (FEV1; MD: 0.09; 95% CI: 0.02, 0.17), forced vital capacity (FVC; MD: 0.13; 95% CI: 0.03, 0.23), maximum inspiratory pressure (MD: 14.43; 95% CI: 8.71, 20.14), maximal expiratory pressure (MD: 15.06; 95% CI: 5.69, 24.43), and QOL (SMD: -0.77; 95% CI: -1.43, -0.11). However, no significant effect of respiratory muscle training on FEV1 /FVC was found (MD: 1.22; 95% CI: -1.61, 4.06). Respiratory muscle training is a positive intervention for improving exercise tolerance, pulmonary function, respiratory muscle strength, and QOL in COPD patients. Further high quality studies are needed to validate the findings of this review.

Indexed as

Chronic obstructive pulmonary diseaseexercise endurancemeta-analysispulmonary functionrespiratory muscle training

Identifiers

PMID41234761
PMCPMC12609738

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.