ArticleBJA open2025
Perioperative cognitive behavioural therapy compared with pain education and mindfulness for chronic postsurgical pain in breast cancer patients with high pain catastrophising characteristics: a randomised, controlled, parallel group clinical trial.
Article in BJA open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04924010 (Effect of Perioperative Cognitive Behavioural Therapy on Chronic Persistent Postsurgical Pain Among Breast Cancer Patients With High Pain Catastrophising Characteristics), which is not on this map. Not yet cited in PubMed.
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The trial behind it
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Effect of Perioperative Cognitive Behavioural Therapy on Chronic Persistent Postsurgical Pain Among Breast Cancer Patients With High Pain Catastrophising Characteristics: A Randomised, Double-blind Clinical Trial
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The incidence of chronic postsurgical pain (CPSP) is relatively high after breast cancer surgery. Psychological factors, especially high pain catastrophising, are predictive of CPSP. Cognitive behavioural therapy (CBT) can reduce anxiety and depression and help emotional self-regulation. We tested the hypothesis that perioperative CBT is more effective than a pain education and mindfulness (PEM) programme at reducing CPSP intensity at 3 months after breast cancer surgery in high pain catastrophising patients. Methods: Women having primary breast cancer surgery were screened ( Results: There were no significant between group differences at 3 months with regard to the primary outcome, BPI average pain intensity score difference (median 25-75%) PEM Conclusions: Delivery of four one-to-one, perioperative CBT or PEM sessions to patients with high pain catastrophising characteristics achieved similar reductions in pain intensity at 3 months after breast cancer surgery. Perioperative psychology might potentially help reduce the incidence of CPSP after breast cancer surgery. Clinical trial registration: NCT04924010.
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