Evidence map›Paper›PMID 41234723›Full record

ArticleFrontiers in oncology2025

3D-printed PEEK versus conventional free fibula flap for jaw reconstruction: a comparative clinical study.

Dongdong Feng, Yuxiang Zhang, Haiwei Guo, Chuanming Zheng, Yining Zhang, Wanchen Zhang, Fangyuan Lai, Jiajie Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dongdong FengOtolaryngology and Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Yuxiang ZhangOtolaryngology and Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Haiwei GuoOtolaryngology and Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Chuanming ZhengOtolaryngology and Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Yining ZhangOtolaryngology and Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Wanchen ZhangOtolaryngology and Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Fangyuan LaiCenter for Plastic and Reconstructive Surgery, Department of Plastic and Reconstructive Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.
Jiajie XuOtolaryngology and Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Aimed to evaluate the application value of polyether ether ketone (PEEK) based on three-dimensional (3D) printing technology for jaw reconstruction. Methods: This study retrospectively analyzed 16 patients who underwent jaw reconstruction in the Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital, from August 2019 to December 2023. A subsequent comparison was made between the effectiveness of free fibula flap (FFF) and PEEK schemes. Result: A total of 16 patients were included in this study. In the FFF group, six male and two female patients (mean age, 40.8 ± 21.2 years) underwent jaw defect reconstruction successfully. However, one patient in this group required the removal of the titanium plate due to uncontrollable infection. In the PEEK group, which consisted of five men and three women (mean age, 56.3 ± 12.6 years), six patients achieved satisfactory outcomes, including accurate jaw restoration and good occlusal function during follow-up, and were successfully discharged. However, two patients in this group experienced secondary infection, which necessitated the removal of the PEEK implants and subsequent salvage reconstruction using FFF. The operative time was significantly shorter in the PEEK group compared to the FFF group ( Conclusion: 3D printing technology enables the fabrication of patient-specific PEEK implants with customized geometries. Owing to its stable biocompatibility, PEEK is suitable for reconstructing complex and irregular jaw defects. As a viable alternative for primary jaw reconstruction, it demonstrates promising clinical application prospects.

Indexed as

3D printing technologyfibula free flapjawPEEKreconstruction

Identifiers

PMID41234723
PMCPMC12605317

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.