ArticleIranian journal of microbiology2025
Nano-based mouthwash containing white basil essential oil a potent alternative for oral hygiene.
Article in Iranian journal of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and Objectives: White basil ( Materials and Methods: Formulations combining white basil essential oil, Tween-80, isopropanol, Labrasol and water were prepared. Particle size, zeta potential, and pH were measured. Stability was evaluated under accelerated (40°C, 75% RH) and stressed (60°C, 75% RH) conditions over three months. Antimicrobial efficacy was assessed via minimum bactericidal concentration (MBC) after 30-second exposure. Results: Characterization of the optimized formulation revealed an average particle size of 128 nm, neutral zeta potential, pH 3.42. Stability testing demonstrated thermodynamic resistance under all storage conditions for three months without phase separation or significant size change. The MBC against Conclusion: Nanodispersion offers a promising strategy for white basil essential oil in mouthwash formulations. The developed formulation shows favorable stability and rapid bactericidal action, supporting further evaluation for clinical and commercial development.
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