Evidence map›Paper›PMID 41234560›Full record

ArticleTranslational lung cancer research2025

The impact of rurality, socioeconomic status, and health literacy on lung cancer screening uptake: a systematic review protocol.

Apeksha Phulgirkar, Aaleyah Kelso, Rashmikaa Ranganathan, Rebecca N Jerome, Jennifer A Lewis, Lucy B Spalluto

Abstract read
In one paragraph

Article in Translational lung cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Apeksha PhulgirkarMaster of Public Health Program, School of Medicine, Vanderbilt University, Nashville, TN, USA.
Aaleyah KelsoMaster of Public Health Program, School of Global Health, Meharry Medical College, Nashville, TN, USA.
Rashmikaa RanganathanMaster of Public Health Program, School of Medicine, Vanderbilt University, Nashville, TN, USA.
Rebecca N JeromeVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Jennifer A LewisGeriatric Research Educational and Clinical Center (GRECC) and the VETWISE-LHS Center of Innovation, VA Tennessee Valley Healthcare System, Nashville, TN, USA.
Lucy B SpallutoGeriatric Research Educational and Clinical Center (GRECC) and the VETWISE-LHS Center of Innovation, VA Tennessee Valley Healthcare System, Nashville, TN, USA.

Funding

CSRD VA I01 CX002686
6 · The paper itself

Abstract

Background: Lung cancer is the leading cause of cancer-related mortality in the United States (U.S.). The United States Preventive Services Task Force (USPSTF) recommends lung cancer screening with low-dose computed tomography (LDCT) for individuals at high risk for lung cancer to improve early detection and survival rates. Despite strong evidence supporting lung cancer screening, its adoption remains low. Participation rates range from only 1% to 16% of those eligible across different geographic regions. Further, rural populations may face significant barriers to lung cancer screening access due to factors such as geographic isolation, socioeconomic status (SES), and health literacy. Methods: We propose a systematic review to examine how rurality, SES, and health literacy independently and collectively influence lung cancer screening utilization rates in the U.S. Using the Sample, Phenomenon of Interest, Design, Evaluation and Research (SPIDER) framework, this review will synthesize findings from research studies published between the years 2014 to 2024. The review will explore the barriers to screening uptake, including limited healthcare infrastructure, financial constraints, and inadequate awareness or understanding of lung cancer screening guidelines. Discussion: The findings of this systematic review are intended to influence policies that enhance accessibility, affordability, and education surrounding lung cancer screening to improve outcomes for rural populations. Registration: PROSPERO Registration: CRD42025644774.

Indexed as

health literacylow-dose computed tomography (LDCT)Lung cancerruralitysocioeconomic status (SES)

Identifiers

PMID41234560
PMCPMC12605193

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.