Evidence map›Paper›PMID 41234492›Full record

ArticleFrontiers in artificial intelligence2025

Quantitative evaluation of meibomian gland dysfunction via deep learning-based infrared image segmentation.

Ziyang Yu, Zhijun Wei, Mini Han Wang, Jiazheng Cui, Jiaxiang Tan, Yang Xu

Abstract read
In one paragraph

Article in Frontiers in artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ziyang YuBeijing Institute of Technology, Zhuhai, China.
Zhijun WeiBeijing Institute of Technology, Zhuhai, China.
Mini Han WangZhuhai Institute of Advanced Technology Chinese Academy of Sciences (CAS), Zhuhai, China.
Jiazheng CuiZhuhai Institute of Advanced Technology Chinese Academy of Sciences (CAS), Zhuhai, China.
Jiaxiang TanSchool of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing, China.
Yang XuSchool of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, numerous advanced image segmentation algorithms have been employed in the analysis of meibomian glands (MG). However, their clinical utility remains limited due to insufficient integration with the diagnostic and grading processes of meibomian gland dysfunction (MGD). To bridge this gap, the present study leverages three state-of-the-art deep learning models-DeepLabV3+, U-Net, and U-Net++-to segment infrared MG images and extract quantitative features for MGD diagnosis and severity assessment. A comprehensive set of morphological (e.g., gland area, width, length, and distortion) and distributional (e.g., gland density, count, inter-gland distance, disorder degree, and loss ratio) indicators were derived from the segmentation outcomes. Spearman correlation analysis revealed significant positive associations between most indicators and MGD severity (correlation coefficients ranging from 0.26 to 0.58;

Indexed as

deep learningdry eye diseaseimage segmentationmeibograpymeibomian gland dysfunction

Identifiers

PMID41234492
PMCPMC12605355

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.