ArticleFrontiers in psychiatry2025
Assessment of depression and anxiety in Tunisian patients with chronic diseases: impact on quality of life and medication adherence.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence, Predictors, and Challenges in the Management of Depression Among Patients on Hemodialysis in the Arab Countries: A Systematic Review.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Pooled it
- Associations of weight change with perceived stress and depression: a nationwide population-based study.Frontiers in psychiatry · 2026Article
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8 authors.
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Abstract
Introduction: Chronic illness affects patients' quality of life and often leads to underdiagnosed psychological issues, which can impact treatment adherence. This study aimed to assess quality of life in Tunisian patients with chronic diseases, screen for anxiety and depression, and evaluate their effect on medication adherence. Methods: We conducted a cross-sectional study including 170 patients consulting at the National Social Security Fund for chronic conditions, from September to November 2022. Quality of life was assessed using the Short Form 12 Health Survey, anxiety and depression using the Hospital Anxiety and Depression scale, and treatment adherence using the Morisky, Green, and Levine scale. Results: Among the 170 patients included in this study, 116 were women (68.2%), with a female-to-male ratio of 2.14. The mean age was 60 years and 5 months ± 9.85 years. The most common conditions were cardiovascular (71.7%), endocrine (64.7%), and pulmonary diseases (40.5%). The prevalences of depression and anxiety were 51.8% and 47%, respectively. Quality of life was impaired, with mean physical and mental scores of 35.05 ± 9.69 and 44.32 ± 11.13, respectively. Anxiety was more prevalent among women (p<0.001) and individuals under 60 years of age (p=0.009). Depression and anxiety were negatively correlated with quality of life. Depressive symptoms were associated with lower levels of treatment adherence (p=0.049). Conclusion: Anxiety and depression were frequent among patients with chronic diseases and were associated with poorer quality of life and lower treatment adherence. These findings underscore the burden of psychological distress in this population and highlight its detrimental effects on both well-being and disease management.
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