Evidence map›Paper›PMID 41234221›Full record

ArticlePCN reports : psychiatry and clinical neurosciences2025

Trends in lifetime controlled drug use and associated risk factors among Japanese Junior High School Students: Findings from Nationwide Surveys, 2016-2024.

Satomi Mizuno, Satoshi Inoura, Toshihiko Matsumoto, Kunihiko Kitagaki, Akihiro Koide, Kenji Takehara, Takuya Shimane

Abstract read
In one paragraph

Article in PCN reports : psychiatry and clinical neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Satomi MizunoDepartment of Drug Dependence Research, National Institute of Mental Health National Center of Neurology and Psychiatry Tokyo Japan.ORCID https://orcid.org/0000-0003-0644-1520
Satoshi InouraDepartment of Drug Dependence Research, National Institute of Mental Health National Center of Neurology and Psychiatry Tokyo Japan.
Toshihiko MatsumotoDepartment of Drug Dependence Research, National Institute of Mental Health National Center of Neurology and Psychiatry Tokyo Japan.ORCID https://orcid.org/0000-0002-7076-2161
Kunihiko KitagakiSocial Pharmacy Laboratory, Faculty of Pharmacy Tokyo University of Pharmacy and Life Sciences Tokyo Japan.
Akihiro KoideRegulatory Science Laboratory Yokohama University of Pharmacy Kanagawa Japan.
Kenji TakeharaDepartment of Health Policy National Centre for Child Health and Development Tokyo Japan.
Takuya ShimaneDepartment of Drug Dependence Research, National Institute of Mental Health National Center of Neurology and Psychiatry Tokyo Japan.ORCID https://orcid.org/0000-0001-8906-6230

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To examine trends in the lifetime prevalence of controlled drug use among Japanese junior high school students (aged 12-15 years) between 2016 and 2024 and to identify associated sociodemographic, behavioral, and psychosocial factors. Methods: We analyzed data from 214,011 students across four nationwide surveys. The outcome was lifetime use of controlled drugs, including marijuana, solvents, methamphetamine, and new psychoactive substances. Predictors included demographic characteristics, substance-related behaviors and attitudes, daily routines, and social relationships. Design-weighted logistic regression was used to estimate the prevalence and assess associated risk factors. Results: The lifetime prevalence of controlled drug use showed a clear decreasing trend over the study period, declining from 0.5% (95% confidence interval [CI]: 0.4-0.5) in 2016 to 0.2% (95% CI: 0.1-0.2) in 2024. Similar downward trends were observed for all substances. While perceived drug access and permissiveness declined, tolerant attitudes toward marijuana slightly increased. Invitations to use drugs also became more common. Risk factors for controlled drug use included male sex, alcohol and tobacco use, permissive attitudes, drug invitations, irregular routines, school dissatisfaction, limited friendships, and poor family communication. The combination of multiple social risk factors, particularly when coupled with school dissatisfaction, social isolation, and limited parental consultation, significantly amplified the likelihood of drug use. Conclusion: This repeated cross-sectional analysis indicated that lifetime use of controlled drugs among Japanese adolescents is rare and continues to decline. However, usage remains concentrated among students with overlapping behavioral and social vulnerabilities. Prevention strategies should therefore prioritize these at-risk groups.

Indexed as

illicit drugsschool‐based surveysocial isolationsubstance use attitudesteenager

Identifiers

PMID41234221
PMCPMC12606039

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.