Evidence map›Paper›PMID 41234218›Full record

ArticlePain reports2025

B-cell lymphoma-extra large expression correlated with protein kinase RNA-like ER kinase and ubiquitination signals in the type 1 diabetes mouse model.

Yu-Yu Kan, Ying-Shuang Chang, Tzu-Ning Chao, Yu-Lin Hsieh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pain reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu-Yu KanSchool of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan.
Ying-Shuang ChangDepartment of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Tzu-Ning ChaoDepartment of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Yu-Lin HsiehDepartment of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.ORCID https://orcid.org/0000-0002-6380-3455

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Diabetes mellitus with pain sensation is referred to as diabetic painful neuropathy (DN). DN development results from endoplasmic reticulum (ER) stress, including the upregulation of ER stress signaling-related molecules and autophagy. B-cell lymphoma-extra large (Bcl- Objectives: To investigate the roles of Bcl- Methods: This report used a single dose of streptozotocin (200 mg/kg) to establish a mouse model of T1DM, and to assay the changes in the expression profile of Bcl- Results: This study discovered the coexpression of Bcl- Conclusions: This study uncovers a new neuropathology underlying T1DM-associated DN: Bcl-

Indexed as

B-cell lymphoma-extra largeDiabetic neuropathyER stressEukaryotic initiation factor 2αProtein kinase RNA-like ER kinaseUbiquitin D

Identifiers

PMID41234218
PMCPMC12611234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.