ArticleJournal of Alzheimer's disease : JAD2025
Associations of lifestyle factors with amyloid pathology in persons without dementia.
Abstract read
In one paragraph
Article in Journal of Alzheimer's disease : JAD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- CSF Glucose-6-Phosphate Isomerase Is a Tau-Related Biomarker Associated with Neurodegeneration and Cognitive Impairment in Alzheimer's Disease.Molecular neurobiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
112 authors.
Julie E OomensAlzheimer Center Limburg, Department of Psychiatry & Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, the Netherlands.
Stephanie Jb VosAlzheimer Center Limburg, Department of Psychiatry & Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, the Netherlands.
Nancy N MaserejianDepartment of Epidemiology, Biogen, Cambridge, MA, USA.
Mercè BoadaAce Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.
Mira DidicAPHM, Timone, Service de Neurologie et Neuropsychologie, Hôpital Timone Adultes, Marseille, France.
Sebastiaan EngelborghsDepartment of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
Tormod FladbyDepartment of Neurology, Akershus University Hospital, Lorenskog, Norway.
Wiesje M van der FlierDepartment of Neurology, Alzheimer Centre Amsterdam, Amsterdam Neuroscience, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Giovanni B FrisoniMemory Clinic, University Hospitals and University of Geneva, Geneva, Switzerland.
Lutz FröhlichDepartment of Geriatric Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Kiran Dip GillDepartment of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Timo GrimmerDepartment of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technical University of Munich (TUM), School of Medicine and Health, Munich, Germany.
Jakub HortDepartment of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
Yoshiaki ItohDepartment of Neurology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Takeshi IwatsuboGraduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Aleksandra Klimkowicz-MrowiecDepartment of Internal Medicine and Gerontology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland.
Susan M LandauHelen Wills Neuroscience Institute, University of California, Berkeley, CA, USA.
Dong Young LeeDepartment of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea.
Alberto LleóCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
Pablo Martinez-LageCenter for Research and Advanced Therapies, CITA-Alzheimer Foundation, Donostia-San Sebastian, Spain.
Alexandre de MendonçaFaculty of Medicine, University of Lisbon, Lisboa, Portugal.
Philipp T MeyerDepartment of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Piero ParchiIstituto delle Scienze Neurologiche di Bologna, IRCCS, Padiglione G, Bologna, Italy.
Matteo PardiniDINOGMI, University of Genoa, Genoa, Italy.
Lucilla ParnettiCentro Disturbi della Memoria, Laboratorio di Neurochimica Clinica, Clinica Neurologica, Università di Perugia, Perugia, Italy.
Julius PoppDepartment of Geriatric Psychiatry, University Hospital of Psychiatry Zürich and University of Zürich, Zürich, Switzerland.
Lorena RamiAlzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic of Barcelona, IDIBAPS, Barcelona, Spain.
Eric M ReimanBanner Alzheimer's Institute, Phoenix, AZ, USA.
Juha O RinneTurku PET Centre, University of Turku, Turku, Finland.
Karen M RodrigueCenter for Vital Longevity, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, TX, USA.
Pascual Sánchez-JuanCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
Isabel SantanaFaculty of Medicine, University of Coimbra, Coimbra, Portugal.
Nikolaos Scarmeas1st Department of Neurology, Aiginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Philip ScheltensDepartment of Neurology, Alzheimer Centre Amsterdam, Amsterdam Neuroscience, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Ingmar SkoogNeuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Reisa A SperlingCenter for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Yaakov SternCognitive Neuroscience Division, Department of Neurology and the Taub Institute, Columbia, New York City, NY, USA.
Sylvia VilleneuveMcConnell Brain Imaging Centre, Montreal Neurological Institute, Montreal, Quebec, Canada.
Gunhild WaldemarDanish Dementia Research Center, Department of Neurology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Jens WiltfangDepartment of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Daniel AlcoleaCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
Ricardo F AllegriDepartment of Cognitive Neurology, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Daniele AltomareNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Randall J BatemanDepartment of Neurology and the Alzheimer's Disease Research Center, Washington University School of Medicine, St Louis, MO, USA.
Simone BaiardiDepartment of Biomedical and Neuromotor Sciences (DiBiNeM), University of Bologna, Bologna, Italy.
Ines BaldeirasFaculty of Medicine, University of Coimbra, Coimbra, Portugal.
Kaj BlennowClinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
Anouk den BraberDepartment of Neurology, Alzheimer Centre Amsterdam, Amsterdam Neuroscience, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Mark A van BuchemDepartment of Radiology, University Medical Center Leiden is the institution, Leiden, the Netherlands.
Min Soo ByunDepartment of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jiří CermanDepartment of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
Kewei ChenBanner Alzheimer's Institute, Phoenix, AZ, USA.
Elena ChipiCentro Disturbi della Memoria, Laboratorio di Neurochimica Clinica, Clinica Neurologica, Università di Perugia, Perugia, Italy.
Gregory S DayDepartment of Neurology, Mayo Clinic in Florida, Jacksonville, FL, USA.
Alexander DrzezgaDepartment of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany.
Laura L EkbladTurku PET Centre, University of Turku, Turku, Finland.
Stefan FörsterDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
Juan ForteaCIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.
Yvonne Freund-LeviSchool of Medical Sciences, Örebro University, Örebro, Sweden.
Lars FringsDepartment of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Eric GuedjNuclear Medicine Department, Aix Marseille University, AP-HM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, Centre Européen de Recherche en Imagerie Médicale (CERIMED), Marseille, France.
Christian G HabeckDepartment of Neurology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.
Ron HandelsAlzheimer Center Limburg, Department of Psychiatry & Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, the Netherlands.
Lucrezia HausnerDepartment of Geriatric Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Sabine HellwigDepartment of Psychiatry and Psychotherapy Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Julio F Jiménez-BonillaDepartment of Nuclear Medicine, Marqués de Valdecilla University Hospital and IDIVAL, Santander, Spain.
Ane Iriondo JuaristiCenter for Research and Advanced Therapies, CITA-Alzheimer Foundation, Donostia-San Sebastian, Spain.
Ramesh KandimallaDepartment of Radiation Oncology, Emory University, Atlanta, GA, USA.
Silke KernDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Bjørn-Eivind S Bordewick KirsebomDepartment of Neurology, University Hospital of North Norway, Tromsø, Norway.
Johannes KornhuberDepartment of Psychiatry and Psychotherapy, University Hospital, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
Nienke LegdeurDepartment of Neurology, Alzheimer Centre Amsterdam, Amsterdam Neuroscience, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Johannes LevinDepartment of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Wolfgang MaierDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.
Marta MarquiéAce Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.
Shinobu MinataniDepartment of Neurology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Silvia Daniela MorbelliDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Barbara MroczkoDepartment of Neurodegeneration Diagnostics, Medical University of Białystok, Białystok, Poland.
Eva NtanasiDepartment of Nutrition and Diatetics, Harokopio University, Kallithea, Athens, Greece.
Catarina Resende de OliveiraCenter for Neuroscience and Cell Biology - CIBB, University of Coimbra, Coimbra, Portugal.
Adelina OrellanaAce Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.
Oliver PetersCharité Universitätsmedizin Berlin-CBF, Berlin, Germany.
Sudesh PrabhakarDepartment of Neurology, Nehru Hospital, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Inez H RamakersAlzheimer Center Limburg, Department of Psychiatry & Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, the Netherlands.
Eloy Rodríguez-RodriguezNeurology Department, Hospital Universitario Marqués de Valdecilla and IDIVAL, University of Cantabria, Santander, CIBERNED, Madrid, Santander, Spain.
Agustín RuizAce Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.
Eckart RütherDepartment of Psychiatry and Psychotherapy, University Medical Center, Georg-August University, Göttingen, Germany.
Jayant SakhardandeCognitive Neuroscience Division, Department of Neurology and the Taub Institute, Columbia, New York City, NY, USA.
Per SelnesDepartment of Neurology, Akershus University Hospital, Lorenskog, Norway.
Dina SilvaFaculty of Medicine, University of Lisbon, Lisboa, Portugal.
Hilkka SoininenDepartment of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.
Luiza SpiruGeriatrics, Gerontology, Old Age Psychiatry, Geroscience, Gerontechnology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Akitoshi TakedaDepartment of Neurology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Charlotte E TeunissenNeurochemistry Lab, Department of Laboratory Medicine, Amsterdam Neuroscience, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Betty M TijmsDepartment of Neurology, Alzheimer Centre Amsterdam, Amsterdam Neuroscience, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Lisa VermuntDepartment of Neurology, Alzheimer Centre Amsterdam, Amsterdam Neuroscience, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Åsa K WallinCognitive disorder research unit, Department of Clinical Sciences, Lund University, Malmö, Sweden.
Wietse WielsFaculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium.
Mary YannakouliaDepartment of Nutrition and Diatetics, Harokopio University, Kallithea, Athens, Greece.
Dahyun YiInstitute of Human Behavioral Medicine, Medical Research Center Seoul National University, Seoul, Republic of Korea.
Anna ZettergrenDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Alzheimer's Disease Neuroimaging Initiative (ADNI)Membership detailed in online Appendix 1.
A4 Study groupMembership detailed in online Appendix 1.
Dominantly Inherited Alzheimer Network (DIAN)Membership detailed in online Appendix 1.
European Prevention of Alzheimer's Dementia (EPAD) consortium, Fundació ACE Healthy Brain Initiative (FACEHBI)Membership detailed in online Appendix 1.
Japan Alzheimer's Disease Neuroimaging Initiative (J-ADNI), Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease (KBASE)Membership detailed in online Appendix 1.
Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) research groupMembership detailed in online Appendix 1.
Rik OssenkoppeleDepartment of Neurology, Alzheimer Centre Amsterdam, Amsterdam Neuroscience, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Frans Rj VerheyAlzheimer Center Limburg, Department of Psychiatry & Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, the Netherlands.
Pieter Jelle VisserAlzheimer Center Limburg, Department of Psychiatry & Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, the Netherlands.
Willemijn J JansenAlzheimer Center Limburg, Department of Psychiatry & Neuropsychology, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, the Netherlands.
Funding
Project 1U19AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI Paul S. Aisen · 2016 to 2026
$226.7MAlzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0MImaging CoreU19AG032438 · NIA · WASHINGTON UNIVERSITY · PI BATEMAN, RANDALL J · 2010 to 2025
$53.9MPET, APOE & the Preclinical Course of Alzheimer's DiseaseR01AG031581 · NIA · BANNER ALZHEIMER'S INSTITUTE · PI CASELLI, RICHARD J., REIMAN, ERIC MICHAEL · 2008 to 2018
$16.6MKBASE2: Korean Brain Aging Study, Longitudinal Endophenotypes and Systems BiologyU01AG072177 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI LEE, DONG YOUNG, NHO, KWANGSIK TIMOTHY · 2021 to 2025
$11.2MImaging CoreU01AG032438 · NIA · WASHINGTON UNIVERSITY · PI XIONG, CHENGJIE · 2008 to 2009
$6.1MCerebral amyloid angiopathy fluid biomarkers evaluation (CAFE)R01NS104147 · NINDS · UNIVERSITY OF RHODE ISLAND · PI VAN NOSTRAND, WILLIAM E. · 2018 to 2022
$3.2MNIA NIH HHS R01 AG031581NIA NIH HHS U01 AG024904NIA NIH HHS U01 AG032438NIA NIH HHS U01 AG072177NIA NIH HHS U19 AG024904NIA NIH HHS U19 AG032438NINDS NIH HHS R01 NS104147
Abstract
BackgroundThe association between lifestyle factors and Alzheimer's disease (AD) pathophysiology remains incompletely understood.ObjectiveThe aim of this study was to assess the association of alcohol consumption, smoking behavior, sleep quality and physical, cognitive, and social activity with cerebral amyloid pathology.MethodsFor this cross-sectional study, we selected participants from the Amyloid Biomarker Study data pooling initiative. We used generalized estimating equations to assess associations of dichotomized lifestyle measures with amyloid pathology.ResultsWe included 9171 participants with normal cognition (NC) and 2555 participants with mild cognitive impairment (MCI) from the Amyloid Biomarker Study. Of participants with NC, 58% were women, 34% were
Indexed as
AmyloidCognitive DysfunctionLife StyleAgedAged, 80 and overAlcohol DrinkingApolipoprotein E4Cross-Sectional StudiesDementiaFemaleHumansMaleMiddle AgedSmokingAmyloidApolipoprotein E4Alzheimer's diseaseamyloidamyloid biomarker studycerebrospinal fluidlifestylepositron emission tomography
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.