Evidence map›Paper›PMID 41233851›Full record

ArticleBMC musculoskeletal disorders2025

A retrospective study of rehabilitation for patients with hemophilia knee osteoarthritis after total knee arthroplasty: a 10 year cohort study.

Zhaokai Jin, Yi Tang, Kun Yan, Tianyou Ma, Hua Huang, Zhongyi Zhang, Xinyu Hu, Peijian Tong, Fuping Pan, Shuaijie Lv

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhaokai Jin *The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang, China.
Yi Tang *The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang, China.
Kun YanThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang, China.
Tianyou MaThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang, China.
Hua HuangThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang, China.
Zhongyi ZhangThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang, China.
Xinyu HuThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang, China.
Peijian TongThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang, China.
Fuping PanThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang, China. 1459157991@qq.com.
Shuaijie LvThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang, China. lvshuaijie1990@zcmu.edu.cn.

Funding

Zhejiang Province Traditional Chinese Medicine Science and Technology Program (Clinical Research Program of Traditional Chinese Medicine) 2024ZL044
6 · The paper itself

Abstract

objectiveRehabilitation is an important means to help hemophilic arthropathy (HA) patients recover joint function after total knee arthroplasty (TKA). This article retrospectively analyzes the experience of rehabilitation therapy.

methodsWe retrospectively analyzed cases from January 2011 to December 2021 in the Bone Injury Center Database of Zhejiang Provincial Hospital of Traditional Chinese Medicine. A total of 50 patients were included, classified according to preoperative range of motion (ROM): 14 with ROM between 0 and 45 degrees, 28 with ROM between 45 and 90 degrees, and 8 with ROM greater than 90 degrees. Recording knee joint function and complications from preoperative to postoperative 24 months.

resultsPatients’ knee joint function improved after rehabilitation. The clinical and functional Knee Society Score (KSS) of 0°-45° group increased from 91.36 ± 7.91 to 102.25 ± 5.75 (P < 0.001), 45°-90° group increased from 102.25 ± 5.75 to 126.64 ± 6.97 (P < 0.001), 45°-90° group increased from 104.13 ± 2.80 to 128.00 ± 3.16 (P < 0.001). ROM of 0°-45° group increased from 54.07 ± 8.44 to 77.86 ± 8.20 (P < 0.001), 45°-90° group increased from 77.75 ± 9.59 to 90.43 ± 5.07 (P < 0.001), 45°-90° group increased from 103.25 ± 5.28 to 109.00 ± 5.58 (P < 0.001), and Visual Analogue Scale (VAS) of 0°-45° group decreased from 5.36 ± 1.01 to 3.86 ± 0.86 (P < 0.001), 45°-90° group decreased from 5.07 ± 0.98 to 3.64 ± 0.95 (P < 0.001), 45°-90° group decreased from 5.38 ± 0.74 to 3.88 ± 0.64 (P < 0.001). In a subgroup analysis, the patients with higher preoperative ROM have higher postoperative ROM and KSS. At the end of follow-up, patients with low preoperative ROM had higher VAS scores than other patients.

conclusionWe recommend conducting a systematic evaluation and pre rehabilitation of patients before TKA surgery, and establishing their psychological expectations, followed by early initiation of postoperative rehabilitation. Furthermore, attention should be paid to psychological counseling for patients to enhance their awareness of autonomous rehabilitation. Additionally, monitoring clotting factor levels and promoting functional recovery of adjacent joints and soft tissues are also crucial aspects to consider.

Indexed as

Arthroplasty, Replacement, KneeHemophilia AOsteoarthritis, KneeAdultAgedFemaleHumansKnee JointMaleMiddle AgedRange of Motion, ArticularRecovery of FunctionRetrospective StudiesTreatment OutcomeHaemophilic arthropathyKnee functionRehabilitationTotal knee arthroplasty

Identifiers

PMID41233851
PMCPMC12616920

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.