Evidence map›Paper›PMID 41233552›Full record

ArticleScientific reports2025

Clinical and environmental investigation of six cases of Chryseobacterium arthrosphaerae infections in a Southern Italian hospital.

Francesco Triggiano, Giuseppina Caggiano, Loredana Capozzi, Stefano Castellana, Giusy Diella, Alessandro Furio, Michele Alberto Cantalice, Anna Lucia Manicone, Antonella Francesca Savino, Adriana Mosca and 10 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Francesco TriggianoHygiene Section, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, 70124, Bari, Italy.
Giuseppina CaggianoHygiene Section, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, 70124, Bari, Italy.
Loredana CapozziExperimental Zooprophylactic Institute of Puglia and Basilicata, 71121, Foggia, Italy.
Stefano CastellanaExperimental Zooprophylactic Institute of Puglia and Basilicata, 71121, Foggia, Italy.
Giusy DiellaHygiene Section, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, 70124, Bari, Italy.
Alessandro FurioBari Policlinico University Hospital, Piazza G. Cesare 11, 70124, Bari, Italy.
Michele Alberto CantaliceBari Policlinico University Hospital, Piazza G. Cesare 11, 70124, Bari, Italy.
Anna Lucia ManiconeBari Policlinico University Hospital, Piazza G. Cesare 11, 70124, Bari, Italy.
Antonella Francesca SavinoHygiene Section, Azienda OU Policlinico of Bari, Piazza G. Cesare 11, 70124, Bari, Italy.
Adriana MoscaMicrobiology Section, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, 70124, Bari, Italy.
Carmela De CarloMicrobiology and Virology Unit, Azienda OU Policlinico of Bari, Piazza G. Cesare 11, 70124, Bari, Italy.
Eleonora SparapanoMicrobiology and Virology Unit, Azienda OU Policlinico of Bari, Piazza G. Cesare 11, 70124, Bari, Italy.
Lidia DalfinoSection of Anesthesiology and Intensive Care Medicine, Department of Precision-Regenerative Medicine and Jonic Area (DiMePRe-J), University of Bari Aldo Moro, Piazza G. Cesare 11, 70124, Bari, Italy.
Annalisa SaracinoClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Bari, 70124, Italy.
Francesco Di GennaroClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Bari, 70124, Italy.
Maria Beatrice PrincipiSection of Gastroenterology, Department of Precision-Regenerative Medicine and Jonic Area (DiMePRe-J), University of Bari Aldo Moro, Piazza G. Cesare 11, 70124, Bari, Italy.
Antonio ParisiExperimental Zooprophylactic Institute of Puglia and Basilicata, 71121, Foggia, Italy.
Maria Teresa MontagnaHygiene Section, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, 70124, Bari, Italy.
Silvio TafuriHygiene Section, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, 70124, Bari, Italy.
Osvalda De GiglioHygiene Section, Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, 70124, Bari, Italy. osvalda.degiglio@uniba.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chryseobacterium spp. are Gram-negative, opportunistic pathogens antibiotic-resistant commonly found in the environment. The aim of this study was to investigate potential sources of Chryseobacterium infections in healthcare settings by comparing clinical and environmental isolates using phenotypic and genotypic analyses. Between June and July 2023, six cases of infection with Chryseobacterium spp. were identified in a hospital in Apulia, southern Italy. Environmental sampling (air, surfaces and water) was performed in parallel with routine clinical investigations. Isolates were subjected to antibiotic susceptibility testing and genotypic analysis using Sanger and Next-Generation Sequencing. Five cases of Chryseobacterium spp. infection were recorded in the Gastroenterology Department (Pavilion A) and one in the Vertebral Surgery Department (Pavilion B). C. indologenes was identified in blood and tracheal aspirate samples using MALDI-TOF MS. Environmental analysis carried out in the pavilions A and B isolated C. indologenes from sink tap in Pavilion B. Subsequently, genome sequencing revealed that Chryseobacterium strains misidentified as C. indologenes were more closely related to C. arthrosphaerae. Genetic analysis confirmed the cluster hypothesis involving four patients from the pavilion A, while no genetic link was found between the environmental and clinical strains. Innovative molecular methods in clinical and environmental investigations have allowed more accurate identification of the etiologic agent and possibly tracing the source of infection in the nosocomial setting. Control measures, such as patient isolation and room disinfection, have prevented the spread of infection.

Indexed as

ChryseobacteriumCross InfectionFlavobacteriaceae InfectionsAgedAnti-Bacterial AgentsFemaleHospitalsHumansItalyMaleMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial AgentsBacteremiaChryseobacterium spp.C. indologenesEnvironmental surveillanceGenome sequencingHospital infections

Identifiers

PMID41233552
PMCPMC12615676

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.