ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Inter-center variation in non-elective removal of central catheters amongst level 4 NICUs.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
objectiveTo quantify inter-center variation (ICV) in non-elective removal (NER) of central venous catheters (CVCs) in level 4 Neonatal Intensive Care Units (NICUs). STUDY
designUsing the Children's Hospitals Neonatal Database (CHND), we identified CVCs in infants admitted 2017-2023. The primary outcome was CVC NER, and the primary exposure was CHND center. We quantified unadjusted and adjusted ICV in NER.
resultWe analyzed 71,865 patients and 135,671 CVCs. Median gestational age was 36 weeks and birth weight 2450 g. Over 50% infants (28,077) received >1 CVC. Centers placed 196-7120 catheters with a median dwell time of 7 (IQR 4-14) days. The overall NER rate was 11.7%, with significant ICV (unadjusted ICV: 3-19%, p < 0.001; adjusted center-level odds of NER: 0.26-2.03, p < 0.001).
conclusionThere is significant ICV in NER between level IV NICUs. Reducing modifiable NER may increase safety for patients with CVCs. Center-specific NER metrics may serve as clinical benchmarks.
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