ArticleScientific reports2025
U shaped association between sleep duration and long term cognitive decline trajectories in a national cohort.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Integrating Sleep, Eating, Bowel Habits, and Physical Activity in Children and Adolescents: A Conceptual Review of the Four Kai Framework.Children (Basel, Switzerland) · 2026Review
- Objective Sleep Measures and Cognition in Middle-Aged and Older Adults: A Cross-Sectional and Longitudinal Analysis in the ALBION Study.Medical sciences (Basel, Switzerland) · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The existing evidence concerning the association between sleep duration and long-term cognitive trajectories remains inconclusive. This cohort study utilized data from the China Health and Retirement Longitudinal Study (CHARLS) spanning from 2011 to 2020, with biennial surveys conducted. Group-based trajectory modeling identified cognitive trajectories over a 9-year period. Multivariable logistic regression, incorporating multiple imputation techniques to address missing data, assessed the association between sleep duration and long-term cognitive function. The sample comprised 8668 participants with a mean age of 56.3 years, of whom 45.7% were female. Among them, 34.24% exhibited cognitive decline, while 65.76% maintained stable cognition. The odds ratios (OR) for incident cognitive decline were 1.17 (95% CI: 1.04-1.31) for individuals with short sleep duration (< 6 h) and 1.57 (95% CI: 1.31-1.89) for those with long sleep duration (> 8 h). Subsequent analysis revealed a U-shaped relationship between sleep duration and incident cognitive decline (nonlinear, p < 0.001). Specifically, when sleep duration was below 7.23 h, an increase in sleep duration significantly reduced the risk of cognitive decline (OR = 0.90, 95% CI: 0.86-0.95). Conversely, when sleep duration equaled or exceeded 7.23 h, an increase in sleep duration significantly elevated the risk of cognitive decline (OR = 1.31, 95% CI: 1.17-1.46). These findings suggest that sleep duration is independently associated with long-term cognitive decline in a U-shaped manner, with a nadir around 7.23 h. Screening and brief counseling for short (< 6 h) and long (> 8 h) sleep, alongside promotion of sleep hygiene and assessment for treatable sleep disorders, may offer scalable strategies to support healthy cognitive aging.
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