Evidence map›Paper›PMID 41233384›Full record

ArticleScientific data2025

Near telomere to telomere genome assembly of Chinese yellow rabbit (Oryctolagus cuniculus).

Xuequn Chen, Chunying Yu, Deqiang Liu, Qiuming Zhong, Jianhua Zhou, Wei Lin, Yanyan Yang, Jindong Xie, Xunli Wang, Sheng Wu and 4 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. A Near-Telomere-to-Telomere Genome Assembly of the Spotted Seal (International journal of molecular sciences · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xuequn Chen *The Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Chunying Yu *The Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Deqiang LiuThe Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Qiuming ZhongThe Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Jianhua ZhouThe Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Wei LinThe Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Yanyan YangThe Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Jindong XieThe Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Xunli WangThe Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Sheng WuFujian Academy of Medical Sciences, Fuzhou, Fujian, 350001, China.
Liping QianFujian Academy of Medical Sciences, Fuzhou, Fujian, 350001, China.
Yao LinThe Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.ORCID 0000-0002-0493-0155
Xiping XieInstitute of Animal Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences, Fuzhou, Fujian, 350013, China.
Zhen HuangThe Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, College of Integrative Medicine, Fujian-Macao Science and Technology Cooperation Base of Traditional Chinese Medicine-Oriented Chronic Disease Prevention and Treatment, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China. zhuang@fjtcm.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oryctolagus cuniculus (Fujian Yellow Rabbit; FJY), the only indigenous rabbit breed in China, known for its yellow coat, adaptability, and higher meat quality. However, comprehensive genomic datasets on O. cuniculus -FJY are lacking. In this study, we assembled the nearly full telomere-to-telomere (T2T) genome of O. cuniculus -FJY, 68% T2T, using PacBio HiFi, ONT ultra-long, and Hi-C data. The 2.88 Gb assembly was anchored into 23 chromosomes (21 autosomes, X and Y), with 99.80% of the sequence successfully assigned to chromosomal positions. Scaffold N50 reached 148.90 Mb, and glires BUSCO completeness of 98.3%. Repeats account for 47.09% of the genome. We identified 22,674 genes, with 99.74% functionally annotated. Additionally, we annotated 1,341 tRNAs, 922 rRNAs, 635 miRNAs, and 2,421 snRNAs. This genome represents the closest T2T rabbit genome and the first successful assembly of the Y chromosome in O. cuniculus. It not only enhances our understanding of the genetic diversity and evolutionary history of the domestication of rabbits, but also provides crucial data support for future breeding research on O. cuniculus-FJY.

Indexed as

GenomeTelomereAnimalsChinaRabbits

Identifiers

PMID41233384
PMCPMC12615707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.