Evidence map›Paper›PMID 41233322›Full record

ArticleNature communications2025

Boosting the brightness of aggregation-caused quenching chromophore-based covalent organic frameworks via energy level matching strategy.

Liang Zhang, Weihang Geng, Xinwen Ou, Shan He, Xiao-Hang He, Wenlang Li, Yantian Jiao, Ziyi Cheng, Ziyi Jin, Jun Qian and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Liang Zhang *State Key Laboratory of Precision and Intelligent Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui, China. zhangliang2025@ustc.edu.cn.ORCID http://orcid.org/0000-0002-5960-8913
Weihang Geng *State Key Laboratory of Extreme Photonics and Instrumentation, International Research Center for Advanced Photonics, Centre for Optical and Electromagnetic Research, College of Optical Science and Engineering, Zhejiang University, Hangzhou, China.
Xinwen Ou *Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.ORCID http://orcid.org/0000-0001-6694-7932
Shan He *Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Xiao-Hang HeState Key Laboratory of Precision and Intelligent Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui, China.
Wenlang LiDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Yantian JiaoDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Ziyi ChengState Key Laboratory of Precision and Intelligent Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui, China.
Ziyi JinState Key Laboratory of Precision and Intelligent Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui, China.
Jun QianState Key Laboratory of Extreme Photonics and Instrumentation, International Research Center for Advanced Photonics, Centre for Optical and Electromagnetic Research, College of Optical Science and Engineering, Zhejiang University, Hangzhou, China. qianjun@zju.edu.cn.ORCID http://orcid.org/0000-0003-2131-3885
Ben Zhong TangDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China. tangbenz@cuhk.edu.cn.ORCID http://orcid.org/0000-0002-0293-964X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most chromophores exhibit an aggregation-caused quenching (ACQ) effect, resulting in minimal or weak emission when incorporated into covalent organic frameworks (COFs). Consequently, the development of luminescent COFs, particularly those utilizing ACQ chromophores, presents both a compelling and formidable challenge. Herein, we report the construction of highly emissive ACQ chromophore-based COFs by an energy level matching strategy. This approach effectively modulates the electronic structures within the COFs, thereby suppressing intralayer charge transfer to ACQ chromophores, such as the imine linkage and dibenzo[g,p]chrysene unit, while simultaneously inhibiting interlayer charge transfer and non-radiative decay pathways. As a result, the undesired ACQ effect is mitigated, enabling the realization of highly emissive COFs. Notably, COF-BT-PhDBC demonstrates high brightness with a solid-state photoluminescence quantum yield of 14.7%, standing among the best ACQ chromophore-based COFs. Furthermore, COF-BT-PhDBC has been successfully utilized for in vivo three-photon fluorescence imaging of murine brain vasculature, achieving an impressive imaging depth of approximately 800 µm.

Identifiers

PMID41233322
PMCPMC12615774

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