Evidence map›Paper›PMID 41233010›Full record

ReviewClinics in perinatology2025

Long-Term Outcomes After Interventions for Infants with Congenital Heart Defects.

Gabriel Perlow, Lazaros Kochilas

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gabriel PerlowChildren's Healthcare of Atlanta; Division of Cardiology, Department of Pediatrics, Emory School of Medicine, Atlanta, GA 30322, USA.
Lazaros KochilasChildren's Healthcare of Atlanta; Division of Cardiology, Department of Pediatrics, Emory School of Medicine, Atlanta, GA 30322, USA. Electronic address: Lazaros.Kochilas@emory.edu.

Funding

Long-term Outcomes after Interventions for Congenital Heart DiseaseR01HL122392 · NHLBI · UNIVERSITY OF MINNESOTA · PI KOCHILAS, LAZAROS K. · 2014 to 2022
$5.2M
Long-term outcomes in patients with single ventricle physiologyR21HL145486 · NHLBI · EMORY UNIVERSITY · PI KOCHILAS, LAZAROS K. · 2019 to 2020
$234k
NHLBI NIH HHS R01 HL122392NHLBI NIH HHS R21 HL145486
6 · The paper itself

Abstract

Congenital heart defects (CHD) affect approximately 1 of every 100 live births in the United States. Advances in surgical and transcatheter interventions since the 1970s have markedly improved survival, with over 85% of affected infants now reaching adulthood. Clinical registries have enabled crucial insights into peri-operative and long-term outcomes. While survival has improved, patients with history of CHD interventions often face comorbidities, such as heart failure, arrhythmias, and neurodevelopmental challenges. Lifelong surveillance is essential, as most interventions do not constitute a cure but an important part of a life-long management of a chronic congenital condition.

Indexed as

Cardiac Surgical ProceduresHeart Defects, CongenitalHeart FailureHumansInfantInfant, NewbornTreatment OutcomeUnited StatesCongenital heart defectsInterventionsLong-term outcomes

Identifiers

PMID41233010
PMCPMC13477680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.