Evidence map›Paper›PMID 41232938›Full record

GuidelineThe European respiratory journal2025

European Respiratory Society and European Society of Thoracic Surgeons clinical practice guideline on fitness for curative intent treatment of lung cancer.

Alessandro Brunelli, Georgia Hardavella, Rudolf M Huber, Thierry Berghmans, Armin Frille, Maria Rodriguez, Ilona Tietzova, Lieven Depypere, Riccardo Asteggiano, Tim Batchelor and 26 more

Abstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in The European respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

36 authors.

Alessandro BrunelliDepartment of Thoracic Surgery, St James's University Hospital, Leeds, UK alexit_2000@yahoo.com.ORCID https://orcid.org/0000-0002-6505-1656
Georgia Hardavella4th-9th Department of Respiratory Medicine, "Sotiria" Athens' Chest Diseases Hospital, Athens, Greece.
Rudolf M HuberDivision of Respiratory Medicine and Thoracic Oncology, Department of Medicine V, Ludwig-Maximilians-University of Munich, Thoracic Oncology Centre Munich, German Centre for Lung Research (DZL CPC-M), Munich, Germany.ORCID https://orcid.org/0000-0001-7041-6368
Thierry BerghmansThoracic Oncology Functional Unit, Institut Jules Bordet, Hôpital Universitaire de Bruxelles, Université Libre de Bruxelles, Brussels, Belgium.
Armin FrilleDepartment of Medicine II (Oncology, Gastroenterology, Hepatology and Respiratory Medicine), University of Leipzig Medical Center, Leipzig, Germany.ORCID https://orcid.org/0000-0003-2843-3863
Maria RodriguezThoracic Surgery Department, Clínica Universidad de Navarra, Madrid, Spain.
Ilona TietzovaFirst Department of Tuberculosis and Respiratory Diseases, General University Hospital in Prague and First Faculty of Medicine, Charles University, Prague, Czech Republic.
Lieven DepypereDepartment of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.
Riccardo AsteggianoInternal Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Tim BatchelorSt Bartholomew's Hospital, London, UK.ORCID https://orcid.org/0000-0003-4103-6061
Adrien CostantiniRespiratory Diseases and Thoracic Oncology Department, Hôpital Ambroise Pare Assistance Publique-Hôpitaux de Paris (AP-HP), Boulogne-Billancourt, France.
Dirk De RuysscherGROW - Research Institute for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
Valerie DurieuxBibliothèque des Sciences de la Santé, Université Libre de Bruxelles, Brussels, Belgium.ORCID https://orcid.org/0000-0002-8975-6562
Corinne Faivre-FinnClinical Oncology, The Christie NHS Foundation Trust, Manchester, UK.ORCID https://orcid.org/0000-0001-5617-9781
Mark K FergusonDivision of Thoracic Surgery, Department of Surgery, University of Chicago, Chicago, IL, USA.
Daniel LangerKU Leuven, Faculty of Movement and Rehabilitation Sciences, Department of Rehabilitation Sciences, Research Group for Rehabilitation in Internal Disorders, Leuven, Belgium.ORCID https://orcid.org/0000-0001-8738-9482
Nandor MarczinDepartment of Anaesthesia, Royal Brompton Hospital, Royal Brompton and Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, London, UK.
Blin NagavciInstitute for Evidence in Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Nuria NovoaDepartment of Thoracic Surgery, University Hospital Puerta de Hierro-Majadahonda, Madrid, Spain.
Cecilia PompiliInstitute for Clinical and Applied Health Research, University of Hull, Hull, UK.ORCID https://orcid.org/0000-0001-6746-5441
Janette RawlinsonLung Cancer Patient Advisory Group, European Lung Foundation, Sheffield, UK.
Annemiek SnoeckxDepartment of Radiology, Antwerp University Hospital and University of Antwerp, Antwerp, Belgium.
Thomy ToniaInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Wouter H van GeffenDepartment of Respiratory Medicine, Medical Center Leeuwarden, Leeuwarden, The Netherlands.
Clare WilliamsEuropean Lung Foundation, Sheffield, UK.ORCID https://orcid.org/0000-0001-9446-0339
Edward J CaruanaDepartment of Thoracic Surgery, Glenfield Hospital, University Hospitals Leicester, Leicester, UK.
Pinar Akin KabalakDepartment of Chest Diseases, University of Health Sciences, Ankara Atatürk Sanatorium Training and Research Hospital, Ankara, Turkey.
Ulrich MansmannDepartment of Medical Information Sciences, Biometry and Epidemiology, Medical Faculty, Ludwig Maximilians University, Munich, Germany.ORCID https://orcid.org/0000-0002-9955-8906
Vincent FalletHopital Tenon Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
Diego Kauffmann-GuerreroDepartment of Medicine V, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
Marianne PaesmansStatistics Department, Institut Jules Bordet, Hôpital Universitaire de Bruxelles, Brussels, Belgium.
Amani Al TawilInstitute for Medical Information Processing, Biometry, and Epidemiology (IBE), Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Nora AlhannoushDivision of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, London, UK.
Andrew W CreamerUCL Respiratory, University College London, London, UK.ORCID https://orcid.org/0000-0002-9314-1210
Ismini KourouniDivision of Pulmonary, Critical Care and Sleep Medicine, Case Western Reserve University (MetroHealth Medical Center), Cleveland, OH, USA.
Torsten Gerriet BlumLungenklinik Heckeshorn, Helios Klinikum Emil von Behring, Berlin, Germany.ORCID https://orcid.org/0000-0003-1216-2157

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A multidisciplinary panel of lung cancer experts with a special interest in functional evaluation of lung cancer patients, and lung cancer patient representatives, has been facilitated by the European Society of Thoracic Surgeons and the European Respiratory Society to provide healthcare professionals with practical and up-to-date recommendations for the assessment of patients' fitness for curative intent treatments for lung cancer. The panel formulated four PICO (population, intervention, comparison and outcomes) questions and seven complementary narrative questions. Both types of questions were assigned to groups of at least two experts. A medical librarian conducted the literature searches, and the authors selected relevant studies based on predefined inclusion criteria. Risk of bias was assessed using the QUIPS (Quality in Prognosis Studies) tool. Data were summarised and the certainty of evidence was assessed with GRADE (Grading of Recommendations, Assessment, Development and Evaluations) and the Evidence to Decisions framework was used to formulate recommendations. A series of multidisciplinary recommendations was formulated about the utilisation of pulmonary function tests, split lung function values, exercise tests, cardiologic testing, and the role of prehabilitation, sublobar resections, risk scores and comorbidities in selecting patients for curative intent treatment.

Indexed as

Lung NeoplasmsEuropeExercise TestHumansPulmonary MedicineRespiratory Function TestsSocieties, MedicalThoracic Surgery

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.