ArticlePloS one2025
Association of socioeconomic disadvantage with operative outcomes for infective endocarditis.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Insurance Status and Quality of Care in Infective Endocarditis: A National Analysis of Disparities in Length of Stay, Discharge, and Mortality.Journal of clinical medicine · 2026Article
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundSocial determinants of health (SDOH) are well-recognized contributors of disparities in cardiovascular disease. Yet, the association of socioeconomic disadvantage with outcomes following operative management of infectious endocarditis (IE) remains ill-defined.
methodsNonelective adult (≥18 years) hospitalizations entailing cardiac valve operations for IE were tabulated from the 2016-2021 Nationwide Readmissions Database. Those facing adverse SDOH, including compromised economic, educational, healthcare, environmental, and social conditions, were categorized as Disadvantaged (others: Non-Disadvantaged). Multivariable regression models were developed to examine the association of socioeconomic disadvantage with key endpoints.
resultsOf an estimated 36,527 hospitalizations, 31.9% were categorized as Disadvantaged with the proportion increasing from 27.0% in 2016 to 34.8% in 2021 (P < 0.001). On average, Disadvantaged was younger (50 [34-64] vs 53 years [37-65], P < 0.001), more frequently insured by Medicaid (33.8 vs 26.4%, P < 0.001), and more commonly underwent isolated tricuspid operations (21.9 vs 13.7%, P < 0.001). Following risk adjustment, Disadvantage remained linked with significantly greater likelihood of acute kidney injury (Adjusted Odds Ratio [AOR] 1.20, 95% Confidence Interval [CI] 1.12-1.29), stroke (AOR 1.25, 95%CI 1.11-1.41), and prolonged mechanical ventilation ≥24 hours (AOR 1.80, 95%CI 1.65-1.96). Further, Disadvantaged was associated with incremental increases in postoperative hospitalization duration (+4.97 days, 95%CI 4.39-5.54) and costs (+$32,900, 95%CI $29,300-36,500) as well as a greater risk of nonelective 90-day readmissions (AOR 1.12, 95%CI 1.03-1.23).
conclusionsAdverse SDOH are independently linked with greater morbidity and resource utilization following surgical management of IE. Efforts are needed to ensure comprehensive SDOH screening upon admission and develop targeted in-hospital interventions to address persistent disparities.
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