Evidence map›Paper›PMID 41231817›Full record

ArticlePloS one2025

Improving detection accuracy of heterogeneity in biological tissues through the combination of modulation-demodulation frame accumulation techniques and enhanced vgg16.

Fulong Liu, Siyuan Huang, Jie Gao, Xin Zhou, Junqi Wang

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fulong LiuXuzhou Medical University, School of Medical Information and Engineering, Xuzhou, Jiangsu, China.ORCID https://orcid.org/0000-0003-3341-6486
Siyuan HuangXuzhou Medical University, School of Medical Information and Engineering, Xuzhou, Jiangsu, China.
Jie GaoXuzhou Medical University, School of Medical Information and Engineering, Xuzhou, Jiangsu, China.
Xin ZhouXuzhou Medical University, School of Medical Information and Engineering, Xuzhou, Jiangsu, China.
Junqi WangXuzhou Medical University, School of Medical Information and Engineering, Xuzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light source has obvious absorption and scattering effects during the transmission process of biological tissues, making it difficult to identify heterogeneities in multi-spectral images. This paper achieves a gradual improvement in the classification accuracy of heterogeneities on multi-spectral transmission images (MTI) through the combination of modulation-demodulation frame accumulation (M_D-FA) techniques and enhanced Visual Geometry Group 16 (VGG16) models. Firstly, experiments are designed to collect MTI of phantoms. Then, the image is preprocessed by different combinations of frame accumulation (FA) and modulation and demodulation (M_D) techniques. Finally, multi-spectral fusion pseudo-color images obtained from U-Net semantic segmentation are inputted into the original and enhanced VGG16 network models for heterogeneous classification. The experimental results show that: While both FA and M_D significantly improved the image quality individually, their combination (M_D-FA) proved superior, yielding the highest signal-to-noise ratio (SNR) and the most accurate heterogeneous classification. Compared to the original VGG16 model, the enhanced VGG16 models gradually improved the classification accuracy. Most importantly, the 3.5 Hz M_D-FA images processed by the Visual Geometry Group 16-Batch Normalization-Squeeze and Excitation-Global Average Pooling (VGG16_BN_SE_GAP) model achieved the highest classification accuracy of 97.57%, significantly outperforming results using FA or M_D alone. In summary, this paper utilizes different combinations of FA and M_D techniques to further improve the accuracy of deep learning networks on multi-spectral images heterogeneous classification, which promotes the clinical application of multi-spectral transmission imaging technology in early breast cancer detection.

Indexed as

Image Processing, Computer-AssistedAlgorithmsHumansPhantoms, ImagingSignal-To-Noise Ratio

Identifiers

PMID41231817
PMCPMC12614575

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.