Trial reportPsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2026
Quality-of-life improvements associated with reductions in cocaine-positive urine drug screens.
Trial report in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Translational medications development for methamphetamine use disorder: A systematic review of preclinical, human laboratory, and clinical research.Pharmacological reviews · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectiveObjectively verified reductions in cocaine use may be a more viable treatment target compared to complete abstinence. However, few studies have examined the associated health benefits of this change. This study assessed how quality-of-life outcomes (psychological functioning, social functioning, sleep) change with reductions in cocaine-positive urine drug screens.
methodParticipants (
resultsOverall, higher proportions of cocaine-negative urine test results were associated with statistically significant, although modest, between- and within-subject changes in several quality-of-life measures, including psychosocial functioning, mental health, and sleep. Participants who reached at least 75% cocaine-negative urine test results during treatment demonstrated improvements in all Short Inventory of Problems-Cocaine outcomes, excluding Total Score.
conclusionsThese findings indicate that reducing cocaine use improves quality-of-life outcomes in people with cocaine use disorder. These results also extend prior research on more robust health improvements that emerge when participants attain 75% negative urine test results over a trial. Future research should explore the extent to which these beneficial outcomes apply to other cocaine use disorder samples, including those with more severe comorbid psychosocial challenges at baseline. (PsycInfo Database Record (c) 2026 APA, all rights reserved).
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.