Comparative analysis of optical properties in amniotic membrane products.

Bryanna J Lee, Jeffrey Tsao, Natalie A Afshari

Abstract readComparative Study

In one paragraph

Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bryanna J LeeShiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California San Diego, 9415 Campus Point Drive, La Jolla, San Diego, CA, 92037, USA.

Jeffrey TsaoShiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California San Diego, 9415 Campus Point Drive, La Jolla, San Diego, CA, 92037, USA.

Natalie A AfshariShiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California San Diego, 9415 Campus Point Drive, La Jolla, San Diego, CA, 92037, USA. naafshari@health.ucsd.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCompare optical properties of amniotic membranes (AM) using a modified photographic-based method.

methodsOptical measures of various AMs (Prokera® Plus, Prokera® Slim, Amniograft®, Ambio2®, Ambio5®) and a Collagen Shield were quantified by examining standardized band pattern images through the AMs. Blur Index (BI) was calculated by comparing standard deviations of gray values, while transparency ratio (TR) was determined by comparing mean peak gray values of white bars viewed through the AMs.

resultsBIs ranged from 0.97% (Ambio2®) to 22.58% (Ambio5®), with 0% signifying minimal blurring. TRs ranged between 0.906 to 1.018, with greater values signifying more brightness. BI and TR showed an inverse correlation (r = - 0.954, 95% CI - 0.984, - 0.871). Thicker AMs generally demonstrated higher BIs. Cross-linking effects were unpredictable.

conclusionTR inversely correlated with BI and thicker AMs generally exhibited higher BIs. This method offers a rapid, cost-effective approach to comparing AM optical qualities, providing insights into patient vision.

Indexed as

AmnionBiological DressingsCollagenHumansCollagenAmniotic membraneBlur indexCorneal surgeryOptical qualityVision

Identifiers

PMID41231423

DOI10.3389/fbioe.2020.613804

PMCPMC12615551

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.