Evidence map›Paper›PMID 41231348›Full record

ArticleThe Cochrane database of systematic reviews2025

Busulfan and melphalan (Bu-Mel) versus carboplatin, etoposide, and melphalan (CEM) conditioning regimens for autologous haematopoietic stem cell transplant in children and young adults with high-risk neuroblastoma.

Aditya Kumar Gupta, Jagdish Prasad Meena, Shivam Bansal, Sanjana Sarangarajan, Manisha Komal, M Jeeva Sankar

Abstract read
In one paragraph

Article in The Cochrane database of systematic reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aditya Kumar GuptaDepartment of Pediatrics (Division of Pediatric Oncology), All India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0002-3730-8944
Jagdish Prasad MeenaDepartment of Pediatrics (Division of Pediatric Oncology), All India Institute of Medical Sciences, New Delhi, India.
Shivam BansalDepartment of Pediatrics (Division of Pediatric Oncology), All India Institute of Medical Sciences, New Delhi, India.
Sanjana SarangarajanDepartment of Pediatrics (Division of Pediatric Oncology), All India Institute of Medical Sciences, New Delhi, India.
Manisha KomalDepartment of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
M Jeeva SankarNewborn Health Knowledge Centre, WHO Collaborating Centre for Training and Research in Newborn Care, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis is a protocol for a Cochrane Review (intervention). The objectives are as follows: To compare the efficacy and safety of busulfan and melphalan (Bu-Mel) conditioning chemotherapy with carboplatin, etoposide, and melphalan (CEM) conditioning chemotherapy for autologous haematopoietic stem cell transplantation in children and young adults (0 to 21 years of age) with high-risk neuroblastoma.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsHematopoietic Stem Cell TransplantationNeuroblastomaTransplantation ConditioningAdolescentBusulfanCarboplatinChildChild, PreschoolEtoposideHumansInfantMelphalanRandomized Controlled Trials as TopicReview Literature as TopicTransplantation, AutologousBusulfanCarboplatinEtoposideMelphalan

Identifiers

PMID41231348
PMCPMC12614202

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.