Evidence map›Paper›PMID 41231333›Full record

ReviewLa Radiologia medica2026

T2 hypointense lesions in the parapharyngeal space: a diagnostic challenge.

Edith Vassallo, Emma Tabone, Reuben Grech, Marco Ravanelli, Ivan Zorza, Valerio Mazza, Giulia Petrilli, Lorenzo Ugga, Davide Farina, Roberto Maroldi and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in La Radiologia medica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Edith VassalloMedical Imaging Department, Mater Dei Hospital, Imsida, MSD2090, Malta.
Emma TaboneUniversity Hospital of Wales, Cardiff and Vale Health Board, Cardiff, UK.
Reuben GrechMedical Imaging Department, Mater Dei Hospital, Imsida, MSD2090, Malta.
Marco RavanelliDepartment of Radiology, University of Brescia, P.Zzale Spedali Civili 1, 25123, Brescia, Italy.
Ivan ZorzaDepartment of Radiology, University of Brescia, P.Zzale Spedali Civili 1, 25123, Brescia, Italy.
Valerio MazzaSanta Chiara Hospital, Largo Medaglie d'oro, 9, 38122, Trento, Italy.
Giulia PetrilliDepartment of Pathology, University of Brescia, P.Zzale Spedali Civili 1, 25123, Brescia, Italy.
Lorenzo UggaDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Miraglia 2, 80138, Naples, Italy. lorenzo.ugga@unicampania.it.ORCID http://orcid.org/0000-0001-7811-4612
Davide FarinaDepartment of Radiology, University of Brescia, P.Zzale Spedali Civili 1, 25123, Brescia, Italy.
Roberto Maroldi *Department of Radiology, University of Brescia, P.Zzale Spedali Civili 1, 25123, Brescia, Italy.
Minerva Becker *Division of Radiology, Diagnostic Department, Geneva University Hospitals, Genève, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The parapharyngeal space is a complex anatomical site in the head and neck which may harbour clinically occult pathology given its deep-seated location. The vast majority of parapharyngeal space lesions are of intermediate or hyperintense signal on T2W sequences. This review focuses on T2 hypointense parapharyngeal space lesions which are rare and may constitute a diagnostic dilemma. We present the differential diagnosis of these lesions, highlighting the pertinent radiological findings and identifying a histological correlation for the low T2 signal. A brief discussion of the physics principles accounting for these imaging features is also included. We propose a diagnostic algorithm to facilitate diagnosis and avoid unnecessary biopsy, whenever possible.

Indexed as

Head and Neck NeoplasmsMagnetic Resonance ImagingParapharyngeal SpaceAlgorithmsDiagnosis, DifferentialHumansFibrous lesionsGranulomatous lesionsMelanomaParapharyngeal spaceT2 hypointense lesions

Identifiers

PMID41231333
PMCPMC12982243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.