Evidence map›Paper›PMID 41231322›Full record

ReviewCurrent neurology and neuroscience reports2025

Continuous Ventricular Irrigation for Intraventricular Hemorrhage.

Emily G Dunbar, Tanvika Vegiraju, Andrew P Carlson

Abstract readReview
In one paragraph

Review in Current neurology and neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily G DunbarDepartment of Neurosurgery, University of Virginia, 1215 Lee St, Charlottesville, VA, 22903, USA.
Tanvika VegirajuUniversity of Virginia School of Medicine, Charlottesville, VA, USA.
Andrew P CarlsonDepartment of Neurosurgery, University of Virginia, 1215 Lee St, Charlottesville, VA, 22903, USA. eqb2ts@uvahealth.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewDespite decades of research, intraventricular hemorrhage (IVH) remains a devastating condition with high morbidity and mortality. Traditional external ventricular drains (EVDs) have long served as the cornerstone of surgical management but are limited by various complications. This review evaluates recent literature on continuous ventricular irrigation as an alternative approach to treating IVH. RECENT

findingsEarly data surrounding continuous ventricular irrigation systems, including retrospective comparative studies and case series are encouraging. However, existing randomized data are limited by small sample size and methodological flaws. Larger, ongoing studies such as ACTIVE and ARCH aim to provide more definitive evidence. Continuous ventricular irrigation offers theoretical and practical advantages over static drainage in IVH patients, including enhanced clot clearance and improved catheter patency, particularly when combined with continuous thrombolytic therapy. Optimized protocols for irrigation rates, medication dosing, and timing are still being investigated. Robust clinical trials are necessary to validate the approach and establish best practices.

Indexed as

Cerebral HemorrhageCerebral Intraventricular HemorrhageCerebral VentriclesTherapeutic IrrigationHumansActive CSF exchangeContinuous irrigationEVDIntraventricular hemorrhageIRRAflowIVH

Identifiers

PMID41231322
PMCPMC12615550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.