Evidence map›Paper›PMID 41231137›Full record

ArticleActa crystallographica. Section D, Structural biology2025

Limiting the effects of radiation damage in MicroED through dose selection during data processing.

Henri Colyn Bwanika, Jingjing Zhao, Gerhard Hofer, Uwe H Sauer, Hongyi Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section D, Structural biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Henri Colyn BwanikaDepartment of Material and Environmental Chemistry, Stockholm University, Stockholm, Sweden.
Jingjing ZhaoDepartment of Material and Environmental Chemistry, Stockholm University, Stockholm, Sweden.
Gerhard HoferDepartment of Material and Environmental Chemistry, Stockholm University, Stockholm, Sweden.ORCID 0000-0002-9248-6989
Uwe H SauerDepartment of Chemistry, Umeå University, Umeå, Sweden.
Hongyi XuDepartment of Material and Environmental Chemistry, Stockholm University, Stockholm, Sweden.

Funding

Knut och Alice Wallenbergs Stiftelse 2018.0237Science for Life Laboratory MicroED@SciLifeLabVetenskapsrådet 2017-05333Vetenskapsrådet 2019-00815
6 · The paper itself

Abstract

Microcrystal electron diffraction (MicroED), also known as three-dimensional electron diffraction (3D ED), allows the collection of diffraction data from submicrometre-sized crystals under low electron-dose conditions. Despite having several advantages over conventional X-ray crystallographic techniques, susceptibility to radiation damage is a great challenge that remains to be solved in MicroED. Similar to X-ray crystallography, radiation damage to the macromolecular crystal structures in MicroED manifests in two forms: global damage that affects the overall order of the crystal lattice and site-specific damage that affects highly sensitive residues and moieties in macromolecules. Traditionally, the unit e

Indexed as

ElectronsCrystallography, X-Raydata processingmacromolecular structuremicrocrystal electron diffractionMicroEDradiation damage

Identifiers

PMID41231137
PMCPMC12809500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.