ArticleActa medica academica2025
Factors Affecting the Quality of Life of Children With Transfusion-Dependent Thalassemia: A Cross-Sectional Study.
Article in Acta medica academica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to identify the factors affecting the quality of life (QoL) of children with transfusion-dependent thalassemia. MATERIALS AND
methodsA cross-sectional study was conducted on 38 hospitalized pediatric patients with thalassemia at two regional hospitals in Indonesia. We used demographic and anthropometric data, as well as the Pediatric Quality of Life Inventory 4.0 Generic Core Scales (PedsQL), to collect the data.
resultsThe median age of the participants was 11 years (range, 2-18), with a median age at diagnosis of 12.5 months (2 - 84). The average hemoglobin (Hb) level was 8.47 g/dl, and 34% of the patients had blood type O. The interval between blood transfusions was 23.74 days, with a median number of transfusions of 200.5 (range, 22 - 405). The median current weight was 25 kg (range, 9.5 - 50 kg). More than half of the fathers (52.6%) and mothers (50%) of the children with thalassemia had completed only elementary school. The mean total QoL score reported by children was 82.69±13.38, and by parents, 82.6±11.27. Among the PedsQL domains, the children reported the highest scores in social functioning (89.86±15.48) and the lowest in school functioning (74.21±18.06). Similarly, parents reported the highest score in social functioning (91.05±12.95) and the lowest in school functioning (78.42±13.9). Multivariable analysis showed that Hb level and current weight were significantly associated with QoL in children with thalassemia.
conclusionsThe QoL of children with thalassemia is generally good and is influenced by their current body weight and Hb levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.