Evidence map›Paper›PMID 41231048›Full record

ReviewEFORT open reviews2025

The role of orthoplastic surgery in musculoskeletal oncology.

Vasileios A Kontogeorgakos, Panayiotis Gavriil, Ioannis Trikoupis, Nikoleta Melissaridou, Dionysios J Papachristou, Panayiotis J Papagelopoulos

Abstract readReview
In one paragraph

Review in EFORT open reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Trends in Lower Limb Orthoplastic Surgery: A Bibliometric Analysis.Plastic and reconstructive surgery. Global open · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vasileios A KontogeorgakosDepartment of Orthopaedic Surgery, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID https://orcid.org/0000-0001-6356-4346
Panayiotis GavriilDepartment of Orthopaedic Surgery, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Ioannis TrikoupisDepartment of Orthopaedic Surgery, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Nikoleta MelissaridouDepartment of Orthopaedic Surgery, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Dionysios J PapachristouDepartment of Anatomy-Histology-Embryology, School of Medicine, University of Patras, Patra, Greece.
Panayiotis J PapagelopoulosDepartment of Orthopaedic Surgery, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The orthoplastic approach refers to an integrated evaluation of the surgical approach, the preoperative planning of surgical margins of resection, the loss of healthy tissue, the size of the resultant tissue defect, the functional defect, the impact of neoadjuvant therapies on local tissue, the patient's comorbidities, and predicted survival in order to decide the most favorable reconstruction option for the individual patient with a sarcoma. Microsurgical techniques are an essential component of the tissue reconstruction ladder. The vascularity of the flap used for reconstruction does not compromise the oncological outcomes, nor does it increase local recurrence or reduce overall survival. Free-vascularized fibula grafts are the most common osseous flaps used for bone defect reconstruction. Adequate fixation is necessary to provide mechanical stability and to increase the rate of primary bone union. Soft tissue wound closure under tension results in wound failure, especially when preoperative radiation therapy is used. Flap reconstruction decreases the rate of wound healing complications, allowing for continuation of adjuvant therapies. Soft-tissue local flaps are frequently used to treat tissue defects with a low complication rate. Plastic reconstruction should be tailored to the specific needs of patients.

Indexed as

flap reconstructionmicrosurgerymusculoskeletal oncologyorthoplastic surgerysarcomawound healing complications

Identifiers

PMID41231048
PMCPMC12139711

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.