Evidence map›Paper›PMID 41230974›Full record

ArticleGlobal health action2025

Socio-economic determinants for reduced uptake of routine childhood vaccination in Afghanistan.

Sayed Ataullah Saeedzai, Jo Knight, Luis Filipe, Sam Moore, Benjamin Loevinsohn

Abstract read
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Article in Global health action, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Sayed Ataullah SaeedzaiFaculty of Health and Medicine, Lancaster University, Lancaster, UK.ORCID 0000-0001-8621-578X
Jo KnightFaculty of Health and Medicine, Lancaster University, Lancaster, UK.ORCID 0000-0002-7148-1660
Luis FilipeFaculty of Health and Medicine, Lancaster University, Lancaster, UK.ORCID 0000-0003-1018-2859
Sam MooreFaculty of Health and Medicine, Lancaster University, Lancaster, UK.ORCID 0000-0001-7786-5342
Benjamin LoevinsohnGavi, The Vaccine Alliance, Geneva, Switzerland.ORCID 0009-0007-7075-5723

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoverage of many routine childhood vaccinations in Afghanistan is low and declining. For instance, only 60% of eligible children received doses of the pentavalent vaccine in 2013-18, and this fell to 51% in 2022/23.

objectiveTo help explain the underlying causes behind this trend, this study aims to identify socio-demographic factors relating to caregivers whose children are either entirely unvaccinated or only partially vaccinated.

methodA secondary analysis of Multi Indictor Cluster survey (MICS) 2022/23 data was conducted that focused on the level of vaccination children had received by the time they reach their first birthday. Children were categorized into unvaccinated, under-vaccinated, and fully vaccinated groups and binary and multinomial logistic regression models were fitted with household characteristics included as explanatory variables.

resultsThe study data comprised 6,178 children aged 12-23 months with a predominance of rural areas (76.2%). In the multinomial analysis, children from Pashto-speaking households had significantly higher odds of being unvaccinated (OR = 3.54, 95% CI: 2.62-4.79) and under-vaccinated (OR = 2.19, 95% CI: 1.74-2.75) compared with those who were fully vaccinated. Maternal education was found to be highly significant, with children whose mothers had no formal education found to be more likely to be under vaccinated (69.1% unvaccinated/under-vaccinated) compared to those with primary education (41.9% unvaccinated/under-vaccinated, adjusted odds ratio: 0.59. 95% CI: 0.43-0.81). Children from the richest households had a full vaccination rate of 55.9% and were less likely to be unvaccinated than fully vaccinated (adjusted odds ratio: 0.22, 95% CI: 0.14-0.35).

conclusionFull vaccination coverage is low, with approximately one-third of Afghan children aged 12-23 months receiving complete vaccine schedules. However, this study shows that rates vary significantly with a range of cultural, economic, and educational factors. These findings suggest that improving maternal healthcare access and education, along with focused outreach in specific demographic groups, may be effective in enhancing immunization coverage.

Indexed as

VaccinationVaccination CoverageAdultAfghanistanFemaleHumansInfantMaleSocioeconomic FactorsAfghanistanChild immunizationimmunization disparitiesinequitiesmaternal educationroutine immunizationsocio-demographic determinantsunder-vaccinated childrenunvaccinated children

Identifiers

PMID41230974
PMCPMC12616657

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