ArticleNMR in biomedicine2025
CEST Contrasts Exhibit Significant Regional Variations in the Human Brain at 3 T.
Article in NMR in biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- CEST Contrasts Exhibit Significant Regional Variations in the Human Brain at 3 T.NMR in biomedicine · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
Chemical exchange saturation transfer (CEST) MRI is a promising molecular imaging technique with established clinical relevance in neuro-oncology. While CEST contrast differences between gray matter (GM) and white matter (WM) are documented, brain region-specific contrast variations remain underexplored. This study investigates the regional variability of CEST contrasts in healthy brains to provide a baseline reference, which could enhance the detection of subtle pathological changes in clinical settings. Ten healthy volunteers (five female, mean age 25 ± 3.1 years) underwent 3D CEST imaging on a 3-T Siemens Prisma scanner. Using a custom segmentation tool, GM and WM regions of interest (ROIs) were automatically selected in the frontal, parietotemporal, and occipital regions and the calcarine sulcus to analyze regional contrast changes for the relaxation-compensated MTR
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