Evidence map›Paper›PMID 41230447›Full record

ArticleFrontiers in pediatrics2025

Repeat ultrasound in pediatric EDs improves appendicitis diagnosis after referral imaging.

Vitaliy Perepelitsa, Jeffrey Ames, Rahul Kaila, Nicholas Sausen, Kari Schneider, Scott Lunas, Bradley Segura, Pablo Avendano, Jeffrey P Louie

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vitaliy PerepelitsaDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, United States.
Jeffrey AmesDepartment of Radiology, University of Minnesota, Minneapolis, MN, United States.
Rahul KailaDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, United States.
Nicholas SausenDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, United States.
Kari SchneiderDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, United States.
Scott LunasClinical and Translational Science Institute, University of Minnesota, Minneapolis, MN, United States.
Bradley SeguraDepartment of Surgery, University of Minnesota, Minneapolis, MN, United States.
Pablo AvendanoDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, United States.
Jeffrey P LouieDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, United States.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
UNIVERSITY OF MINNESOTA CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE (UMN CTSI)UL1RR033183 · NCRR · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2011 to 2011
$8.9M
NCATS NIH HHS UL1 TR000114NCRR NIH HHS UL1 RR033183
6 · The paper itself

Abstract

Background: Acute appendicitis is a leading cause of surgical emergencies in children, with ultrasound (US) emerging as a preferred diagnostic tool due to its lack of radiation and cost-effectiveness. However, the accuracy of US is highly operator-dependent and may vary between general referring emergency departments (EDs) and specialized pediatric EDs. Objective: To compare the diagnostic sensitivity and specificity of US performed at referring EDs vs. a pediatric ED in identifying acute appendicitis. Methods: A retrospective study analyzed pediatric patients aged <18 years who underwent US at referring EDs and were transferred to a pediatric ED for repeat imaging between July 2018 and July 2023. Data collected included US findings, surgical pathology, white blood cell count, and patient disposition. Sensitivities of the US were calculated and compared between settings. Results: Among 64 children included, the US at the pediatric ED demonstrated higher sensitivity (85.2%) compared to referring EDs (51.9%) ( Conclusion: US performed at pediatric EDs exhibited superior diagnostic accuracy for appendicitis compared to referring EDs, likely due to operator expertise and enhanced imaging protocols. Efforts to standardize training and improve resources at referring EDs may reduce diagnostic disparities and unnecessary interventions.

Indexed as

appendicitisdiagnostic accuracypediatric emergencyreferring emergency departmentultrasound

Identifiers

PMID41230447
PMCPMC12602418

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.