Evidence map›Paper›PMID 41230397›Full record

ArticleEuropean heart journal open2025

Mitral Transcatheter edge-to-edge repair rivals surgery for survival despite less complete correction: a systematic review and metanalysis of randomized and propensity score matching studies.

Gianluca Di Pietro, Riccardo Improta, Antonio Lattanzio, Alessandro Roscioli, Lucia Ilaria Birtolo, Marco Tocci, Riccardo Colantonio, Gennaro Sardella, Silvio Fedele, Natalia Pavone and 3 more

Abstract read
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In one paragraph

Article in European heart journal open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. First quinquennium completed: highlights fromEuropean heart journal open · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gianluca Di PietroDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Riccardo ImprotaDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Antonio LattanzioDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Alessandro RoscioliDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Lucia Ilaria BirtoloDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Marco TocciDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Riccardo ColantonioDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Gennaro SardellaDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Silvio FedeleInterventional Cardiology Unit, Sandro Pertini Hospital, Via dei Monti TIbrutini 385, Rome 00158, Italy.
Natalia PavoneDepartment of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli, Rome 00168, Italy.
Wael SaadeDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Fabio MiraldiDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.
Massimo ManconeDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, La Sapienza University of Rome, Viale del Policlinico 155, Rome 00161, Italy.ORCID https://orcid.org/0000-0002-0881-7299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To compare outcomes of patients with severe mitral regurgitation (MR) after m-TEER and surgery. Methods and results: PubMed, Scopus, and Google Scholar databases were searched for randomized controlled trials and propensity score matching studies comparing mid-term outcomes of m-TEER vs. surgical valve repair. All-cause of death, rehospitalization for heart failure, mitral reintervention, NYHA class at clinical follow-up and grade ≥ 3 at echocardiographic follow-up were the outcomes of interest. Additional sensitivity analyses were performed to account for heterogeneity. Nine studies (2 RCT and 7 propensity score matching studies) with a total of 23 825 patients (m-TEER group = 11 970; surgery group = 11 855) were included. Surgery and m-TEER were associated with comparable rates of all-cause mortality at a median follow-up of 18 months (RR 1.02, 95%CI 0.77-1.37, Conclusion: In patients with severe MR, m-TEER resulted in comparable outcomes for all-cause deaths compared to surgery, although the latter was associated with reductions in heart failure rehospitalization, reintervention and MR residual rates at a median 18-month follow-up.

Indexed as

ComparisonMid-term outcomesmitral regurgitationSurgeryTranscatheter edge-to-edge

Identifiers

PMID41230397
PMCPMC12604465

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.