ArticleCrohn's & colitis 3602025
Rate of Participation in a Second Randomized Clinical Trial and Factors Associated with the Likelihood of Participation among IBD Patients who already Experienced a Randomized Clinical Trial.
Article in Crohn's & colitis 360, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
10 authors.
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Abstract
Background: To investigate the rate of participation in a second trial among inflammatory bowel disease (IBD) patients and to identify factors influencing their likelihood of re-engagement. Methods: Retrospective, single-center study. Multivariate logistic regression was used to identify factors associated with re-participation. Results: A total of 29.0% participated in a second trial. In ulcerative colitis, distance >100 km from the clinic and steroid use before the first trial were associated with reduced re-participation. In Crohn's disease (CD), long-standing disease and reimbursement during the first trial were associated with increased re-participation; previous CD-related surgery was associated with reduced re-participation. Conclusions: Understanding factors affecting re-participation in IBD trials is crucial to improving patient involvement in research.
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