Evidence map›Paper›PMID 41230336›Full record

ReviewCurrent epidemiology reports2025

The Role of Glucagon-Like Peptide-1 Receptor Agonists in Post ST-Segment Elevation Myocardial Infarction Care: A Scoping Review.

Leticia Alves Soares, Cynthia Paniagua, Julie Nguyen, Ajla Kojic, Elena Rose Sanfrey, Madison Emilee Reyome, Liliana Aguayo, Elisabeth Lilian Pia Sattler

Abstract readReview
In one paragraph

Review in Current epidemiology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Observational
  3. A systematic review and meta-analyses of glucagon-like peptide-1 receptor agonists in acute myocardial infarction.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leticia Alves SoaresDepartment of Nutritional Sciences, College of Family and Consumer Sciences, University of Georgia, Athens, GA USA.ORCID 0000-0002-9254-8318
Cynthia PaniaguaUniversity of Georgia College of Pharmacy, Athens, GA USA.
Julie NguyenUniversity of Georgia College of Pharmacy, Athens, GA USA.
Ajla KojicUniversity of Georgia College of Pharmacy, Athens, GA USA.
Elena Rose SanfreyUniversity of Georgia College of Pharmacy, Athens, GA USA.
Madison Emilee ReyomeUniversity of Georgia College of Pharmacy, Athens, GA USA.
Liliana AguayoNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA USA.
Elisabeth Lilian Pia SattlerDepartment of Nutritional Sciences, College of Family and Consumer Sciences, University of Georgia, Athens, GA USA.ORCID 0000-0002-6379-7892

Funding

Effect of Dietary Approaches to Stop Hypertension (DASH) Diet on Heart Failure Status in Older AdultsR21AG070765 · NIA · UNIVERSITY OF GEORGIA · PI SATTLER, ELISABETH LILIAN PIA · 2023 to 2024
$429k
NIA NIH HHS R21 AG070765
6 · The paper itself

Abstract

Purpose of review: This scoping review synthesizes current evidence on glucagon-like peptide-1 receptor agonist (GLP-1RA) use after ST-elevation myocardial infarction (STEMI), highlighting their potential as adjunctive therapy. Recent findings: Ten studies investigated exenatide and liraglutide in adults with STEMI, evaluating imaging, clinical, mechanistic, and safety outcomes. GLP-1RA use was safe and well tolerated. Exenatide demonstrated improvements in infarct size, myocardial salvage, and cardiac function, although two trials in broader STEMI populations reported no post-infarction improvements. Across three trials, liraglutide was associated with improved myocardial salvage, infarct size, left ventricular ejection fraction, stroke volume and no-reflow, supported by favorable biomarker changes, but without significant reductions in major cardiovascular events. Summary: While most existing evidence is based on studies with limited generalizability, GLP-1RA use shows promise in improving post-STEMI outcomes. The consistent benefits reported support the need for larger, multicenter trials to clarify GLP-1RA role in cardioprotection and long-term outcomes.

Indexed as

CardioprotectionCardiovascular outcomesExenatideGLP-1 receptor agonistsLiraglutideST-elevation myocardial infarction

Identifiers

PMID41230336
PMCPMC12602557

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.