Evidence map›Paper›PMID 41230333›Full record

ArticleClinical case reports2025

Co-Occurrence of Endogenous and Exogenous Cushing's Syndromes: Does "Double Cushing Syndrome" Really Exist? A Case Report.

Reza Amani-Beni, Atiyeh Karimi Shervedani, Bahar Darouei, Matin Noroozi, Maryam Heidarpour

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Reza Amani-BeniHeart Failure Research Center, Cardiovascular Research Institute Isfahan University of Medical Sciences Isfahan Iran.ORCID https://orcid.org/0000-0002-8383-6676
Atiyeh Karimi ShervedaniSchool of Medicine Isfahan University of Medical Sciences Isfahan Iran.ORCID https://orcid.org/0000-0002-6383-8017
Bahar DaroueiHeart Failure Research Center, Cardiovascular Research Institute Isfahan University of Medical Sciences Isfahan Iran.ORCID https://orcid.org/0000-0002-5269-0061
Matin NorooziSchool of Medicine Isfahan University of Medical Sciences Isfahan Iran.ORCID https://orcid.org/0009-0002-8087-9555
Maryam HeidarpourIsfahan Endocrine and Metabolism Research Center Isfahan University of Medical Sciences Isfahan Iran.ORCID https://orcid.org/0000-0002-4809-4072

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Double Cushing syndrome exists: exogenous steroid use can mask concurrent adrenal hypercortisolism. When symptoms persist and cortisol remains high after tapering or stopping prescribed glucocorticoids, an endogenous source is likely. Early recognition with ACTH testing, dexamethasone suppression, and adrenal imaging reduces misdiagnosis, favors timely surgery, and supports safe tapering.

Indexed as

adrenocortical adenomacase reportcushing syndromedouble cushingglucocorticoids

Identifiers

PMID41230333
PMCPMC12602253

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.