ReviewCureus2025
Role of Arterial Blood Gas in Risk Stratification of Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease in the Emergency Department: A Systematic Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Vertical Displacement Index and Early Treatment-Related Physiological Improvement in Acute Respiratory Failure: An Exploratory Ultrasound-Based Study.Advances in respiratory medicine · 2026Observational
- Article
- Development and evaluation of a clinical prediction model for in-hospital mortality in patients with acute exacerbation of chronic obstructive pulmonary disease.Journal of thoracic disease · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute exacerbations of chronic obstructive pulmonary disease are a leading cause of emergency department visits and hospital admissions, associated with high morbidity, mortality, and healthcare costs. Accurate risk stratification in the emergency department is vital for identifying patients at risk of deterioration and guiding decisions regarding intensive care unit admission or ventilatory support. Arterial blood gas analysis remains the gold standard for assessing respiratory failure, providing direct measurements of potential of hydrogen (pH), partial pressure of carbon dioxide in arterial blood (PCO₂), and partial pressure of oxygen in arterial blood (PaO₂), as well as the fraction of inspired oxygen (PaO₂/FiO₂). This systematic review, based on five eligible studies with a total sample size of 1,305 patients, found that arterial blood gas derangements such as acidosis, hypercapnia, and impaired oxygenation consistently predicted poor outcomes, including increased mortality and need for invasive ventilation. Compared to clinical scores and venous blood gas analysis, arterial blood gas offered more precise insights into ventilatory compromise and gas exchange abnormalities. These findings support arterial blood gas as an indispensable tool in the early risk stratification of acute exacerbation of chronic obstructive pulmonary disease. patients in the emergency department, complementing existing clinical models and improving prognostic accuracy. Larger multicenter studies are warranted to validate arterial blood gas-integrated prediction frameworks and optimize triage strategies in this high-risk population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.