ArticleCureus2025
Impact of Preoperative Nutritional Status on Postoperative Outcomes in Elective Brain Tumor Surgery: A Retrospective Cohort Study in the Philippines.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionMalnutrition, encompassing undernutrition and overnutrition, is a modifiable risk factor for adverse surgical outcomes. While extensive literature links nutritional deficits to poor perioperative outcomes in general surgery, the role of nutrition in elective neurosurgery remains insufficiently characterized, particularly in low- and middle-income countries. This study examined the relationship between preoperative nutritional status and postoperative outcomes in patients undergoing elective brain tumor surgery in the Philippines.
methodsA retrospective cohort study was conducted among adult patients (18-60 years) who underwent elective craniotomy for brain tumor excision at Vicente Sotto Memorial Medical Center (VSMMC) between December 2021 and December 2022. Patients were stratified by body mass index (BMI) into undernourished (<18.5 kg/m
resultsA total of 94 patients were included: six undernourished, 44 well-nourished, and 44 overnourished. Undernourished patients experienced significantly higher mortality compared to well-nourished patients (p=0.0176), while overnourished patients exhibited the highest absolute mortality (7%). No significant differences were observed in infection rates or hospital stay across groups.
conclusionPreoperative malnutrition is associated with increased in-hospital mortality in elective brain tumor surgery. Routine nutritional assessment and optimization should be incorporated into preoperative planning to improve neurosurgical outcomes.
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