ArticleFrontiers in bioengineering and biotechnology2025
Impact of BMI, osteoporosis, and disc degeneration on post-UBE lumbar stability: a finite element analysis of nonlinear synergistic effects.
Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- BMI as an Independent Determinant of Spinal Alignment in Degenerative Scoliosis.Diagnostics (Basel, Switzerland) · 2026Article
- Advances in biomechanical modeling of lumbar spine diseases and tumors: gaps, opportunities, and AI integration.Frontiers in bioengineering and biotechnology · 2026Review
- Effect of body mass index and disc degeneration on lumbar biomechanics after unilateral biportal endoscopy-unilateral laminectomy bilateral decompression for lumbar spinal stenosis: a finite element study.Frontiers in bioengineering and biotechnology · 2026Article
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9 authors.
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Abstract
Objective: The aim of this study is to quantify the independent and combined biomechanical effects of increased BMI, osteoporosis, and disc degeneration on lumbar segmental stability after UBE decompression, thereby informing preoperative risk stratification and guiding optimized postoperative rehabilitation protocols. Methods: A high-fidelity 3D finite-element model of the L3-S1 lumbar spine was developed using CT data of a healthy 31-year-old male volunteer in ANSYS APDL 13.0. This model was used to simulate segmental mechanics after UBE decompression. Four BMI levels (22.86, 26.12, 29.39, 32.65 kg/m Results: 1. Single-factor effects. With increasing BMI, intradiscal pressure (IDP) at L4-L5 rose by ∼9-12% in non-degenerated discs and loading shifted posteriorly; in degenerated discs, IDP remained lower overall, whereas annular (disc-internal) stress and facet-joint von Mises stress increased. Severe osteoporosis increased vertebral axial-compressive displacement by ∼55% and peak facet-joint stress by ∼48%, indicating reduced structural stiffness and uneven load distribution. Progressive disc degeneration at the index level reduced IDP, most in axial rotation (∼70%), followed by flexion (∼65%) and lateral bending (∼63%), with extension showing the smallest decrease (∼12%); 2. Synergistic effects. Under high BMI (32.65 kg/m Conclusion: This finite-element study demonstrated that the coexistence of disc degeneration, osteoporosis, and elevated body mass index markedly increases posterior-element loading and disc-internal stresses after unilateral biportal endoscopic decompression. Changes in range of motion were modest overall and tended to decrease when degeneration was combined with osteoporosis, creating a pseudo-stability state in which elevated internal stress is not reflected by gross segmental motion. These findings highlight the importance of considering body weight, bone quality, and disc health together when evaluating postoperative spinal stability and suggest that stress-based assessments may provide a more reliable indicator of hidden instability risk than motion measurements alone.
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