Risk factors and clinical outcomes of serum

Background: Lung transplantation (LTx) remains a life-saving intervention for patients with end-stage lung diseases, yet complications such as infections, rejection, and thromboembolic events hinder long-term outcomes. Methods: This retrospective study analyzed 293 lung transplant recipients at Northwestern University from January 2018 to June 2023. Patients were stratified based on AGA positivity, and demographic, intraoperative, and postoperative outcomes were compared. The association between AGA positivity, postoperative complications, and survival outcomes was evaluated using Cox proportional hazards and logistic regression models. Results: AGA positivity was detected in 24% of patients, primarily within the first 100 days post-transplant. AGA-positive patients had significantly higher rates of respiratory infections (88.7% Conclusions: Serum AGA positivity is an early biomarker for increased infectious and thrombotic complications in lung transplant recipients. Routine AGA surveillance in post-transplant management may facilitate early identification of high-risk patients, allowing for timely interventions. Further prospective studies are warranted to assess the utility of AGA monitoring in optimizing lung transplant outcomes.