ArticleJournal of thoracic disease2025
Comparisons of respiratory mechanics in patients under different variations of noisy pressure support ventilation during ventilator weaning.
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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14 authors.
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Abstract
Background: Compared with conventional pressure support ventilation (PSV), noisy PSV offers a certain degree of pressure variability, which might benefit the process of weaning from mechanical ventilation. We investigated respiratory mechanics under different levels of variation during the weaning phase in patients receiving noisy PSV to identify the optimal level of variation. Methods: This self-controlled before-and-after study of mechanically ventilated patients in the weaning phase was conducted from September 2020 to October 2022. Each eligible patients received noisy PSV with 0%, 15%, 25%, or 35% variation in a random order. Their respiratory mechanics were collected 1 h after the pressure variation level was switched and compared. Results: The study found that noisy PSV significantly improved patients' respiratory system compliance at variation levels of 25% and 35% (0% Conclusions: Pressure variation at level of 25% or 35% could improve patients' respiratory system compliance and shorten the inspiratory trigger delay time, potentially being optimal in noisy PSV during the weaning phase from mechanical ventilation.
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