ArticleJournal of thoracic disease2025
Impact of sarcopenia on early surgical outcomes in elderly patients following lung cancer surgery: a prospective cohort study.
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05346185 (Association of Preoperative Sarcopenia on Postoperative Outcomes After Lung Cancer Surgery), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association of Preoperative Sarcopenia on Postoperative Outcomes After Lung Cancer Surgery: Prospective Observational Study
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sarcopenia, characterized by reduced muscle mass, strength, and physical performance, has been linked to poor surgical outcomes. Its prevalence increases markedly with age and has been associated with various adverse health conditions in the elderly, including mental health issues like cognitive impairment, quality of life and depression. However, its impact based on international criteria remains unclear in elderly patients undergoing lung cancer surgery. Therefore, we aimed to prospectively evaluate the association between sarcopenia, defined by international guidelines, and postoperative outcomes, as well as geriatric mental health, in this population. Methods: The LUng CAncer Surgery in sarcoPENia patients with old age (LUCAS-PEN) study (ClinicalTrials.gov identifier NCT05346185) prospectively enrolled patients aged ≥70 years undergoing curative lung cancer surgery. Sarcopenia was defined using the Asian Working Group for Sarcopenia (AWGS) criteria. The primary outcome was postoperative complication rates. Propensity score matching (PSM, 1:4) was performed to reduce selection bias. Geriatric mental health was assessed using the Korean version of the Geriatric Depression Scale (GDS-K), the Korean version of the EuroQoL 5-Dimension 5-Level (EQ-5D-5L), EuroQoL Visual Analog Scale (EQ-VAS), and the Korean version of the Montreal Cognitive Assessment (K-MoCA). Results: Among 400 patients, 357 completed all assessments, and 24 (6.7%) were diagnosed with sarcopenia. Compared to non-sarcopenic patients, the sarcopenia group had a lower body mass index (22.73±2.63 Conclusions: This is the first large prospective study to evaluate sarcopenia according to international guidelines for lung cancer surgery. In this prospective study applying AWGS criteria, sarcopenia was not associated with increased early postoperative complications in elderly patients undergoing lung cancer surgery. However, sarcopenia was linked to poorer mental health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.