Evidence map›Paper›PMID 41229744›Full record

ArticleJournal of thoracic disease2025

Bronchodilator response as an independent predictor of severity in bronchiectasis.

Yu Ri Kang, Hyun Lee, Hayoung Choi, Seung Won Ra, Yeon-Mok Oh, Ki Hyun Seo, Jae Sung Choi, Ho Sung Lee, Jiwon Lyu, Jihye Lee and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Yu Ri KangDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.ORCID https://orcid.org/0000-0001-5749-2040
Hyun LeeDivision of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-1269-0913
Hayoung ChoiDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-4812-0653
Seung Won RaDivision of Pulmonary Medicine, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.ORCID https://orcid.org/0000-0002-2458-8414
Yeon-Mok OhDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0116-4683
Ki Hyun SeoDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Jae Sung ChoiDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Ho Sung LeeDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Jiwon LyuDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Jihye LeeDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.ORCID https://orcid.org/0000-0001-8737-8847
Jin-Young KimDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.ORCID https://orcid.org/0000-0002-1261-7312
Kyeong-Deok KimDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Ju Ock NaDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bronchodilator response (BDR) is occasionally observed in patients with bronchiectasis. However, clinical implications of BDR of bronchiectasis remain unclear. This multicenter observational cohort study aimed to compare clinical characteristics and severity in bronchiectasis between patients with BDR and without BDR. Methods: We collected data from the Korean Multicenter Bronchiectasis Audit and Research Collaboration (KMBARC) registry, a multicenter observational cohort of non-cystic fibrosis bronchiectasis. We reviewed the medical records of 709 patients who underwent spirometry. We defined BDR as forced expiratory volume in one second (FEV Results: Of the 709 patients, 7.3% exhibited BDR. Patients with BDR showed worse pulmonary function than those without BDR, both at baseline (FEV Conclusions: In bronchiectasis, BDR is associated with poorer lung function, more frequent exacerbation, and increased disease severity.

Indexed as

Bronchiectasisbronchodilator response (BDR)exacerbationpulmonary function test (PFT)severity

Identifiers

PMID41229744
PMCPMC12603552

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.