Evidence map›Paper›PMID 41229742›Full record

ArticleJournal of thoracic disease2025

Efficacy and safety of self-expandable metallic stent on benign tracheobronchial stenosis: a systematic review and meta-analysis.

Mingyue Fan, Shiyue Li, Wanyuan Rao, Xiaobo Chen, Zhuquan Su

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mingyue Fan *State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Shiyue Li *State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Wanyuan RaoState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xiaobo ChenState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zhuquan SuState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The safety and efficacy of self-expandable metallic stent (SEMS) in the management of benign tracheobronchial stenosis (TBS) remain elusive. This study aimed to provide comprehensive insights into the efficacy and safety of SEMS in treating benign TBS. Methods: We conducted a meta-analysis to elucidate the safety and efficacy of the SEMS in benign TBS. Data on related trials were obtained by doing a literature search in PubMed, Cochrane Library, Web of Science and Embase. Random-effect models were used to calculate the efficacy and incidence of complication of SEMS treatment. Results: Data of 797 participants who received 1,236 SEMS during 26.0±13.5 months of follow-up period were included and analyzed. The main causes of benign TBS included tracheotomy (32.8%), anastomotic stenosis after transplantation or lobectomy (31.3%), tracheal intubation (18.1%), and other benign diseases (17.8%). The total effective rate of SEMS in the treatment of benign TBS was 56.4%, but varied from different etiologies: iatrogenic injury 41.5%, tuberculous infection 83.3%, autoimmune disease 46.2%, and external compression 75%, respectively. The average time of stents placement was 6.59±4.96 months, while the success rate of stent removal was 98.7%. The overall incidence of complications after stent implantation was 45%, including airway restenosis 16.7%, granulation tissue hyperplasia 27.9%, mucus retention 19%, stent migration 20.1%, and stent rupture 25.7%. Airway stent-related mortality was rarely occurred. Conclusions: SEMS could serve as a relatively effective and safe treatment for benign TBS with intensive observation and follow-up.

Indexed as

airway stenosisefficacymeta-analysissafetySelf-expandable metallic stent (SEMS)

Identifiers

PMID41229742
PMCPMC12603481

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.