ArticleEuropean journal of case reports in internal medicine2025
Morgagni-Stewart-Morel Syndrome Presenting as Acute Neurological and Respiratory Distress.
Article in European journal of case reports in internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Morgagni-Stewart-Morel syndrome (MSMS) is an uncommon disorder characterized by internal frontal hyperostosis, obesity, neuropsychiatric symptoms, and often associated endocrine abnormalities, notably hypothyroidism. Acute presentations are rare and can pose diagnostic challenges, especially in the prehospital setting. We describe a rare acute presentation of Morgagni-Stewart-Morel syndrome (MSM) involving neurological deterioration and respiratory failure, highlight the importance of early recognition and multidisciplinary management in improving outcomes. Case presentation: A 62-year-old woman presented with sudden-onset severe neurological impairment accompanied by acute respiratory distress, initially identified by prehospital emergency medical services. Prompt airway management, including endotracheal intubation and mechanical ventilation, enabled stabilization and urgent transfer to hospital care. Neuroimaging revealed characteristic internal frontal bone thickening, confirming the diagnosis of MSMS. A multidisciplinary approach targeting the neurological, endocrine, and respiratory components led to progressive clinical improvement and a favourable recovery. Conclusion: This case underscores the critical importance of early recognition of MSMS in acute, life-threatening presentations. Awareness of this rare syndrome among prehospital and emergency clinicians can facilitate timely intervention and improve patient outcomes. LEARNING POINTS: Morgagni-Stewart-Morel syndrome can exceptionally present with acute neurological and respiratory compromise, not just chronic neuropsychiatric symptoms. The presence of internal frontal hyperostosis, even if incidental, should prompt evaluation for underlying endocrine and neurological dysfunction.Timely airway management and correction of hormonal imbalances are essential to survival and recovery.Multidisciplinary collaboration is crucial in managing complex cases of Morgagni-Stewart-Morel syndrome, especially in acute settings where diagnosis is challenging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.