ArticleComputational and structural biotechnology journal2025
Novel rapid screening device for carotid artery stenosis using video motion analysis: From concept to product.
Article in Computational and structural biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Stroke is the leading cause of death worldwide. Carotid artery stenosis (CAS) is an early indicator of stroke, as well as a risk factor for vascular diseases. Currently, the preferred choice among non-invasive diagnosis tools for assessing CAS severity is carotid Doppler ultrasound; however, it is impractical for use in screening. In this study, the PulStroke project was initiated in our laboratory to transform the video motion analysis (VMA) developed by the authors into a commercial product using a user-centric design approach, with the goal of completing CAS screening with ease. A user takes a 20-second video clip with the PulStroke device, and with just one simple screen touch, the video clip is recorded and automatically uploaded to a cloud server for the assessment of CAS risk. VMA analyzes the video clip, and a risk report is sent to the user's account in 5 min. This process is achieved with an automated system featuring hardware integration and streamlined operation flow via backend/frontend software architecture. This paper presents the methodology used to advance the technology readiness level from 1 to 6, highlighting the evolution of the device and method, called the PulStroke as a potential brand name, from concept to product. As part of the technology maturity evaluation, the PulStroke was tested on target users, i.e., medical and non-medical professionals, for the user experience and post-screening feedback. Most users found the PulStroke to be fully functional and easy to use, and the satisfaction rate was higher than 88 %. The PulStroke device could be incorporated into future clinical practice to provide the general public with quick and cost-effective CAS screening for the first time.
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