Evidence map›Paper›PMID 41229574›Full record

ArticleUrology annals

Trifecta outcomes to assess the feasibility of local anesthesia for benign prostate hyperplasia minimally invasive surgical treatments.

Alberto Olivero, Sinan Khadhouri, Erika Palagonia, Paolo Dell'Oglio, Stefano Tappero, Barend Dreyer, Aldo Massimo Bocciardi, Alberto Caviglia, Antonio Galfano, Feras Al Jaafari and 3 more

Abstract read
In one paragraph

Article in Urology annals. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alberto OliveroDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Sinan KhadhouriDepartment of Urology, School of Medicine, University of St. Andrews, St Andrews, UK.
Erika PalagoniaDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Paolo Dell'OglioDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Stefano TapperoDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Barend DreyerDepartment of Urology, NHS Fife, Victoria Hospital, Kirkcaldy, UK.
Aldo Massimo BocciardiDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Alberto CavigliaDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Antonio GalfanoDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Feras Al JaafariDepartment of Urology, School of Medicine, University of St. Andrews, St Andrews, UK.
Bhaskar K SomaniDepartment of Urology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Amelia PietropaoloEuropean Association of Urology-Young Academic Urologists Urolithiasis and Endourology Working Group, Arnhem, Netherlands.
Silvia SeccoDepartment of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Minimally invasive surgical treatments (MISTs) are many promising approaches for the management of benign prostate hyperplasia (BPH) that might be performed under local anesthesia (LA) and have same-day discharge. To address the feasibility and efficacy of LA for BPH-MIST, a specific trifecta was conceptualized and tested: (1) no intraoperative complications, (2) reduced intraoperative pain, and (3) same-day discharge. Materials and Methods: We prospectively collected data from patients who underwent Rezum, Urolift, and iTIND treatments from January 01, 2023, to February 28, 2024, on an international database. All the patients received a local administration of two anesthetic gels in the urethra before the procedure; selected patients, in addition, received a transperineal anesthetic injection in the periprostatic space or transurethrally with a Schelin Catheter (SC) injection directly in the prostatic lobes. Reduced intraoperative pain was defined as <5 on the visual analogue scale (VAS range: 0-10). Results: Overall, 156 patients were included in the study. Median age was 63.5 (interquartile range [IQR]: 56-70) years. Eleven patients (7.0%) had diabetes, and 29 (18.6%) received anticoagulant medication. Ten patients (6.4%) had indwelling catheters. The median prostate size was 45 ml (IQR: 34-60). Forty-eight patients underwent Urolift (30.8%), 70 (44.8%) Rezum, and 38 (24.4%) iTIND. The transperineal block and the SC were used in 21 patients (13.5%) and 32 (20.5%) patients, respectively, with 103 (66%) patients receiving only the anesthetic gels in the urethra. Performing MIST in pure LA achieved the trifecta outcome in 122 patients (78.2%). Six patients (3.8%) had intraoperative complications. One hundred and thirty patients (83.3%) experienced reduced intraoperative pain (<5 on VAS). One hundred and 47 (94.2%) patients were discharged on the same day of the procedure. Conclusions: LA for MIST in BPH is feasible, with excellent success rates and reduced pain, as trifecta outcomes were achieved.

Indexed as

Benign prostate hyperplasiai-TINDlocal anesthesiaminimally invasive surgical treatmentsRezumSchelin CatheterUrolift

Identifiers

PMID41229574
PMCPMC12604718

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.