Evidence map›Paper›PMID 41229504›Full record

ArticleFrontiers in oncology2025

Colonic metastasis of a huge soft uterine leiomyoma in a postmenopausal woman: a case report.

JianXin Tang, RuiBo Xu, XiaoYu Xi, Ying Liu, ZengFang Hao, JieXian Du, XiaoLi Du

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In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

JianXin Tang *Department of Gynecology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
RuiBo Xu *Department of Gynecology, Handan First Hospital, Handan, Hebei, China.
XiaoYu Xi *Department of Gynecology, Peking University People's Hospital, Beijing, China.
Ying LiuDepartment of Gynecology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
ZengFang HaoDepartment of Pathology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
JieXian DuDepartment of Gynecology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
XiaoLi DuDepartment of Gynecology, Shijiazhuang Hospital of traditional Chinese Medicine, Shijiazhuang, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: .Uterine leiomyomas are the most common benign tumors of the female reproductive system, arising from the overgrowth of smooth muscle tissue within the uterus. Typically, they present as solid, spherical masses that are firmer than the surrounding uterine muscle layer. Onset generally occurs between the ages of 30 and 50, with these tumors often located in the uterine body or cervix. Some women may experience gradual tumor enlargement, accompanied by symptoms such as vaginal bleeding, lower abdominal pain, frequent urination, and constipation. In such instances, surgical treatment should be considered the first choice. Case summary: In this case, A 59-year-old woman presented with a large, soft, and irregularly shaped uterine leiomyoma, formed by the fusion of hundreds of smaller fibroids, which had metastasized to the sigmoid colon.Immunohistochemical analysis further demonstrated that benign uterine leiomyomas may present with morphological features, consistency, and an invasive growth pattern akin to malignant tumors. Innovations: Uterine leiomyomas are benign tumors that rarely metastasize; however, case reports have documented instances of distant metastasis. Conclusion: The purpose of this study is to report a case of a uterine leiomyoma with intestinal metastasis, analyze its rare characteristics and invasive growth pattern, and enhance the understanding of this tumor.

Indexed as

a huge uterine fibroidsbenign metastasizing leiomyomadegeneration of uterine fibroidsmyoma fusionsigmoid mesentery metastasis

Identifiers

PMID41229504
PMCPMC12602207

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